Association between Dental Amalgam Filling and Essential Tremor: A Nationwide Population-Based Case Control Study in Taiwan.
case-control study
dental amalgam fillings
essential tremor
nationwide population
Journal
International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455
Informations de publication
Date de publication:
27 01 2020
27 01 2020
Historique:
received:
31
12
2019
revised:
23
01
2020
accepted:
24
01
2020
entrez:
5
2
2020
pubmed:
6
2
2020
medline:
18
9
2020
Statut:
epublish
Résumé
Essential tremor (ET) is a common neurological disorder and the most common movement disorder. Low-level occupational exposure to mercury vapor is known to be a crucial factor that increases the risk of tremor. Dental amalgam is one of the main sources of mercury in those who possess amalgam restorations. However, the relationship between ET and amalgam filling (AMF) is not quite clear. The purpose of this study was to investigate the association between AMF and the risk of ET using a population-based administrative databank. The data for this study were sourced from the Taiwanese National Health Insurance Research Database (NHIRD). A retrospective case-control study was conducted using this databank from 2000 to 2013. Case and control groups were matched by sex, age, urbanization level, monthly income, and Charlson comorbidity index using the propensity score method with a 1:1 ratio. In this study, 3008 cases and 3008 controls were included. The results from this nationwide population-based case-control study did not indicate any association between ET and AMF in Taiwan. Although the results were not significantly statistical, the findings may be worthy to be valued.
Identifiants
pubmed: 32012693
pii: ijerph17030780
doi: 10.3390/ijerph17030780
pmc: PMC7037675
pii:
doi:
Substances chimiques
Dental Amalgam
8049-85-2
Mercury
FXS1BY2PGL
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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