Molecular Mechanisms of the Interactions of
drug delivery
pHPMA
plasma proteins
polymeric nanoparticles
stealth effect
Journal
Pharmaceutics
ISSN: 1999-4923
Titre abrégé: Pharmaceutics
Pays: Switzerland
ID NLM: 101534003
Informations de publication
Date de publication:
28 Jan 2020
28 Jan 2020
Historique:
received:
20
11
2019
revised:
14
01
2020
accepted:
26
01
2020
entrez:
5
2
2020
pubmed:
6
2
2020
medline:
6
2
2020
Statut:
epublish
Résumé
The binding of plasma proteins to a drug carrier alters the circulation of nanoparticles (NPs) in the bloodstream, and, as a consequence, the anticancer efficiency of the entire nanoparticle drug delivery system. We investigate the possible interaction and the interaction mechanism of a polymeric drug delivery system based on
Identifiants
pubmed: 32013056
pii: pharmaceutics12020106
doi: 10.3390/pharmaceutics12020106
pmc: PMC7076460
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Grantová Agentura České Republiky
ID : 17-009735
Organisme : Grantová Agentura České Republiky
ID : 15-10527J
Organisme : Deutsche Forschungsgemeinschaft
ID : Pa771/17-1
Organisme : Grantová Agentura, Univerzita Karlova
ID : UNCE 204025/2012
Organisme : Ministry of Education, Youth and Sports of the Czech Republic
ID : LTC17065
Organisme : Ministry of Education, Youth and Sports of CR
ID : POLYMAT LO1507
Organisme : Grantová Agentura České Republiky
ID : 17-13283S
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest.
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