Ischaemic stroke in young adults: a global perspective.


Journal

Journal of neurology, neurosurgery, and psychiatry
ISSN: 1468-330X
Titre abrégé: J Neurol Neurosurg Psychiatry
Pays: England
ID NLM: 2985191R

Informations de publication

Date de publication:
04 2020
Historique:
received: 11 11 2019
revised: 10 01 2020
accepted: 13 01 2020
pubmed: 6 2 2020
medline: 18 8 2020
entrez: 5 2 2020
Statut: ppublish

Résumé

Ischaemic stroke at young age is an increasing problem in both developing and developed countries due to rising incidence, high morbidity and mortality and long-term psychological, physical and social consequences. Compared with stroke in older adults, stroke in young adults is more heterogeneous due to the wide variety of possible underlying risk factors and aetiologies. In this review, we will provide an overview of the global variation in the epidemiology of stroke in young adults, with special attention to differences in geography, ethnicity/race and sex, as well as traditional and novel risk factors for early-onset ischaemic stroke, such as air pollution. Understanding global differences is an important prerequisite for better region-specific prevention and treatment of this devastating condition.

Identifiants

pubmed: 32015089
pii: jnnp-2019-322424
doi: 10.1136/jnnp-2019-322424
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

411-417

Subventions

Organisme : NINDS NIH HHS
ID : R01 NS100178
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS105150
Pays : United States

Informations de copyright

© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: AMT is a junior staff member of the Dutch Heart Foundation, project title: “life after ischaemic stroke in young adults” (grant number 2016T044). F-EDL has received the Innovational Research Incentive grant (016-126-351) and the Clinical established investigator Dutch Heart Foundation grant (2014T060). JP has received funding for research on stroke in the young from the Academy of Finland (318075) and Helsinki and Uusimaa Hospital District (TYH2018318). SK effort on this project was partly supported by VA RR&D N1699-R and NINDS R01NS100178 and R01NS105150.

Auteurs

Esther Boot (E)

Department of Neurology, Radboud Univerisity Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Centre for Neuroscience, Nijmegen, The Netherlands.

Merel Sanne Ekker (MS)

Department of Neurology, Radboud Univerisity Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Centre for Neuroscience, Nijmegen, The Netherlands.

Jukka Putaala (J)

Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland.

Steven Kittner (S)

Department of Neurology, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Frank-Erik De Leeuw (FE)

Department of Neurology, Radboud Univerisity Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Centre for Neuroscience, Nijmegen, The Netherlands.

Anil M Tuladhar (AM)

Department of Neurology, Radboud Univerisity Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Centre for Neuroscience, Nijmegen, The Netherlands Anil.Tuladhar@radboudumc.nl.

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