Vitiligo: Mechanisms of Pathogenesis and Treatment.

Animals Autoimmunity Biomarkers Cytokines / metabolism Disease Management Disease Susceptibility Humans Immunologic Memory Vitiligo / diagnosis
IL-15 JAK inhibition autoimmunity immune resident memory vitiligo

Journal

Annual review of immunology
ISSN: 1545-3278
Titre abrégé: Annu Rev Immunol
Pays: United States
ID NLM: 8309206

Informations de publication

Date de publication:
26 04 2020
Historique:
pubmed: 6 2 2020
medline: 12 8 2021
entrez: 5 2 2020
Statut: ppublish

Résumé

Vitiligo is an autoimmune disease of the skin that targets pigment-producing melanocytes and results in patches of depigmentation that are visible as white spots. Recent research studies have yielded a strong mechanistic understanding of this disease. Autoreactive cytotoxic CD8

Identifiants

DOI: 10.1146/annurev-immunol-100919-023531 PMID: 32017656
pubmed: 32017656
doi: 10.1146/annurev-immunol-100919-023531
doi:

Substances chimiques

Biomarkers 0
Cytokines 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

621-648

Auteurs

Michael L Frisoli (ML)

University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA; email: michael.frisoli@umassmed.edu, kingsley.essien@umassmed.edu, john.harris@umassmed.edu.

Kingsley Essien (K)

University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA; email: michael.frisoli@umassmed.edu, kingsley.essien@umassmed.edu, john.harris@umassmed.edu.

John E Harris (JE)

University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA; email: michael.frisoli@umassmed.edu, kingsley.essien@umassmed.edu, john.harris@umassmed.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Vitiligo: Mechanisms of Pathogenesis and Treatment.
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Auto-immunité › Vitiligo: Mechanisms of Pathogenesis and Treatment.
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Vitiligo: Mechanisms of Pathogenesis and Treatment.
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Vitiligo: Mechanisms of Pathogenesis and Treatment.
questionsmedicales.fr › Administration des services de santé › Gestion des soins aux patients › Prise en charge de la maladie › Vitiligo: Mechanisms of Pathogenesis and Treatment.
questionsmedicales.fr › Phénomènes physiologiques › Constitution physique › Prédisposition aux maladies › Vitiligo: Mechanisms of Pathogenesis and Treatment.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Vitiligo: Mechanisms of Pathogenesis and Treatment.
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Immunité acquise › Mémoire immunologique › Vitiligo: Mechanisms of Pathogenesis and Treatment.
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Hypopigmentation › Vitiligo › Vitiligo: Mechanisms of Pathogenesis and Treatment.