Comparative Fluoride Release and Antimicrobial Analysis of Commercial and Experimental Bioactive Glass/Nano-Oxide-Based Dentifrices.
Journal
European journal of dentistry
ISSN: 1305-7456
Titre abrégé: Eur J Dent
Pays: Germany
ID NLM: 101303672
Informations de publication
Date de publication:
Feb 2020
Feb 2020
Historique:
pubmed:
6
2
2020
medline:
6
2
2020
entrez:
5
2
2020
Statut:
ppublish
Résumé
The objectives were to measure fluoride release and assess the antimicrobial behavior of fluoride-doped nano bioactive glass (F-nBG) and nano zinc oxide (ZnO)-enriched novel dentifrices. Experimental dentifrices were synthesized by incorporating ZnO nanoparticles and F-nBG (1.5 wt% and 4 wt%) as active ingredients. The fluoride release behavior of suspensions and elutes of samples were analyzed by ion selective electrode. Antimicrobial activity and minimum bactericidal concentration against The fluoride release behavior of experimental dentifrices was higher than that of commercial dentifrices and was dependent on filler loading. The fluoride release was more from suspensions than elutes. Zones of inhibition (ZOIs) and minimum bactericidal concentration values for novel dentifrices showed direct proportionality with filler loading, and effectiveness was exhibited against both strains. Experimental dentifrices exhibited effective antibacterial potential, which could possibly be due to release of sufficient fluoride and zinc ions in aqueous media from F-nBG and ZnO present in their formulations. Combination of F-nBG and ZnO may provide a multi-benefit approach for simultaneously treating early white spot lesions, reducing bacterial growth, and providing core plaque control.
Identifiants
pubmed: 32018280
doi: 10.1055/s-0040-1701292
pmc: PMC7069735
doi:
Types de publication
Journal Article
Langues
eng
Pagination
38-44Déclaration de conflit d'intérêts
None declared.
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