Paronychia and Periungual Granulation as a Novel Side Effect of Ibrutinib: A Case Report.
Ibrutinib
Paronychia
Periungual granulation
Side effect
Journal
Skin appendage disorders
ISSN: 2296-9195
Titre abrégé: Skin Appendage Disord
Pays: Switzerland
ID NLM: 101670617
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
received:
19
07
2019
accepted:
28
08
2019
entrez:
6
2
2020
pubmed:
6
2
2020
medline:
6
2
2020
Statut:
ppublish
Résumé
Ibrutinib is an oral covalent inhibitor of the Bruton's tyrosine kinase pathway and is approved for the treatment of B-cell malignancies including chronic lymphocytic leukaemia, mantle cell lymphoma, and Waldenström's macroglobulinaemia. It is generally a drug of choice for high-risk patients with indolent lymphomas. The safety profile of ibrutinib appears to be tolerable, with well-known side effects such as infections and haematologic complications. Additionally, dermatological adverse reactions with ibrutinib therapy have been reported to encompass maculopapular rash and hair/nail abnormalities. Here, we present a case of ibrutinib-induced paronychia and periungual granulation in a 40-year-old woman. To the best of our knowledge, this is the third description of ibrutinib-induced paronychia and periungual granulation.
Identifiants
pubmed: 32021859
doi: 10.1159/000502986
pii: sad-0006-0032
pmc: PMC6995981
doi:
Types de publication
Case Reports
Langues
eng
Pagination
32-36Informations de copyright
Copyright © 2019 by S. Karger AG, Basel.
Déclaration de conflit d'intérêts
None of the authors declare any financial support or relationships that may pose a conflict of interest regarding this paper.
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