Functional role of c-Jun NH
dynein
kinesin
lysosomal transport
Journal
Drug discoveries & therapeutics
ISSN: 1881-784X
Titre abrégé: Drug Discov Ther
Pays: Japan
ID NLM: 101493809
Informations de publication
Date de publication:
08 Mar 2020
08 Mar 2020
Historique:
pubmed:
6
2
2020
medline:
17
3
2020
entrez:
6
2
2020
Statut:
ppublish
Résumé
Lysosomes are involved in many cellular functions, and in turn lysosomal dysfunction underlies a variety of diseases, including cancer and neurodegenerative diseases. Lysosomes are distributed broadly in the cytoplasm and can move throughout the cell in kinesin- and dynein-dependent manners. Although many mechanisms of lysosomal transport have been reported, how lysosomal transport is regulated has yet to be fully elucidated. In this study we analyzed c-Jun NH
Identifiants
pubmed: 32023558
doi: 10.5582/ddt.2020.01001
doi:
Substances chimiques
Adaptor Proteins, Signal Transducing
0
DCTN1 protein, human
0
Dynactin Complex
0
SPAG9 protein, human
0
Mitogen-Activated Protein Kinase 9
EC 2.7.1.24
Kinesins
EC 3.6.4.4
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM