Mitophagy in Acute Kidney Injury and Kidney Repair.
acute kidney injury
kidney repair
mitochondria
mitophagy
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
01 02 2020
01 02 2020
Historique:
received:
11
12
2019
revised:
24
01
2020
accepted:
25
01
2020
entrez:
7
2
2020
pubmed:
7
2
2020
medline:
11
2
2021
Statut:
epublish
Résumé
Acute kidney injury (AKI) is a major kidney disease characterized by rapid decline of renal function. Besides its acute consequence of high mortality, AKI has recently been recognized as an independent risk factor for chronic kidney disease (CKD). Maladaptive or incomplete repair of renal tubules after severe or episodic AKI leads to renal fibrosis and, eventually, CKD. Recent studies highlight a key role of mitochondrial pathology in AKI development and abnormal kidney repair after AKI. As such, timely elimination of damaged mitochondria in renal tubular cells represents an important quality control mechanism for cell homeostasis and survival during kidney injury and repair. Mitophagy is a selective form of autophagy that selectively removes redundant or damaged mitochondria. Here, we summarize our recent understanding on the molecular mechanisms of mitophagy, discuss the role of mitophagy in AKI development and kidney repair after AKI, and present future research directions and therapeutic potential.
Identifiants
pubmed: 32024113
pii: cells9020338
doi: 10.3390/cells9020338
pmc: PMC7072358
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Références
J Recept Signal Transduct Res. 2019 Jun;39(3):235-242
pubmed: 31538845
JCI Insight. 2019 Dec 5;4(23):
pubmed: 31639106
Arch Toxicol. 2016 Nov;90(11):2779-2792
pubmed: 26659566
Autophagy. 2008 Apr;4(3):354-6
pubmed: 18623629
Nature. 2008 Dec 4;456(7222):605-10
pubmed: 19052620
Cond Med. 2018 Aug;1(5):239-246
pubmed: 30338314
J Biol Chem. 2007 Dec 7;282(49):35803-13
pubmed: 17928295
Nat Rev Mol Cell Biol. 2016 Apr;17(4):213-26
pubmed: 26956194
Exp Cell Res. 2018 Aug 1;369(1):27-33
pubmed: 29704468
Immunity. 2014 Jun 19;40(6):924-35
pubmed: 24931121
Int J Biol Macromol. 2019 Nov 1;140:568-576
pubmed: 31442509
Autophagy. 2020 Jan;16(1):176-178
pubmed: 31679452
Front Physiol. 2019 Sep 25;10:1225
pubmed: 31607953
Autophagy. 2013 Feb 1;9(2):124-37
pubmed: 23295650
EBioMedicine. 2019 Mar;41:384-394
pubmed: 30803933
J Cell Biol. 2010 Apr 19;189(2):211-21
pubmed: 20404107
Kidney Int. 2012 Mar;81(5):477-85
pubmed: 22157656
Nat Rev Mol Cell Biol. 2011 Jan;12(1):9-14
pubmed: 21179058
J Clin Invest. 2011 Oct;121(10):4003-14
pubmed: 21881206
Biochim Biophys Acta. 2015 Oct;1853(10 Pt B):2797-801
pubmed: 25634658
Nature. 2016 Mar 24;531(7595):528-32
pubmed: 26982719
Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F1119-F1128
pubmed: 29846105
Front Physiol. 2015 Apr 08;6:109
pubmed: 25904870
Kidney Int. 2017 Nov;92(5):1071-1083
pubmed: 28890325
Oncotarget. 2017 Mar 28;8(13):20988-21000
pubmed: 28423497
Life Sci. 2019 Oct 15;235:116828
pubmed: 31479679
Kidney Int. 2013 Apr;83(4):568-81
pubmed: 23325082
J Clin Invest. 2015 May;125(5):1873-85
pubmed: 25822020
Int Rev Cell Mol Biol. 2018;340:209-344
pubmed: 30072092
Redox Biol. 2019 Sep;26:101254
pubmed: 31229841
Arch Toxicol. 2014 Jun;88(6):1249-56
pubmed: 24859930
Methods. 2015 Mar;75:141-50
pubmed: 25484341
Life Sci. 2019 Feb 1;218:165-184
pubmed: 30578866
Cell Death Differ. 2009 Jul;16(7):939-46
pubmed: 19229244
Intensive Care Med. 2013 Jun;39(6):987-97
pubmed: 23443311
Int J Mol Sci. 2019 Aug 21;20(17):
pubmed: 31438500
Free Radic Biol Med. 2019 Jan;130:379-396
pubmed: 30439416
Cell Death Differ. 2013 Jan;20(1):31-42
pubmed: 22743996
Nat Rev Nephrol. 2015 May;11(5):264-76
pubmed: 25643664
Kidney Int. 2015 Jan;87(1):137-50
pubmed: 24963915
Am J Physiol Renal Physiol. 2012 Apr 1;302(7):F853-64
pubmed: 22160772
Nat Rev Nephrol. 2017 Mar;13(3):169-180
pubmed: 28138128
Biomaterials. 2019 Aug;211:57-67
pubmed: 31085359
Adv Exp Med Biol. 2017;982:529-551
pubmed: 28551805
Oxid Med Cell Longev. 2016;2016:9460462
pubmed: 28119765
Clin Kidney J. 2015 Oct;8(5):548-59
pubmed: 26413280
Semin Nephrol. 2015 Jan;35(1):108-19
pubmed: 25795504
Cell. 2011 Nov 11;147(4):728-41
pubmed: 22078875
Exp Cell Res. 2017 Jan 15;350(2):390-397
pubmed: 28024839
Nat Cell Biol. 2012 Jan 22;14(2):177-85
pubmed: 22267086
Mech Ageing Dev. 2016 Jan;153:30-40
pubmed: 26814678
Prog Neurobiol. 2013 Jul-Aug;106-107:33-54
pubmed: 23827971
J Pharmacol Exp Ther. 1997 Feb;280(2):638-49
pubmed: 9023274
Cell. 2019 Jun 13;177(7):1682-1699
pubmed: 31199916
J Pineal Res. 2019 Mar;66(2):e12542
pubmed: 30516280
Compr Physiol. 2017 Sep 12;7(4):1407-1424
pubmed: 28915329
Autophagy. 2014 Jul;10(7):1346-7
pubmed: 24905224
J Am Soc Nephrol. 2016 Nov;27(11):3356-3367
pubmed: 27000065
Am J Physiol Renal Physiol. 2014 Jun 1;306(11):F1318-26
pubmed: 24671334
Cell Physiol Biochem. 2018;51(5):2359-2376
pubmed: 30537740
Autophagy. 2016;12(4):689-702
pubmed: 27050458
Hum Mol Genet. 2011 Mar 1;20(5):867-79
pubmed: 21138942
Cell Res. 2014 Jan;24(1):24-41
pubmed: 24366339
Immunology. 2010 Sep;131(1):9-17
pubmed: 20586810
Redox Biol. 2019 Jan;20:38-45
pubmed: 30292083
J Am Soc Nephrol. 2016 May;27(5):1288-99
pubmed: 26860342
J Am Soc Nephrol. 2017 May;28(5):1437-1449
pubmed: 27881606
Nat Cell Biol. 2010 Feb;12(2):119-31
pubmed: 20098416
Front Pharmacol. 2014 Nov 05;5:244
pubmed: 25414669
Nephron Clin Pract. 2014;127(1-4):42-5
pubmed: 25343819
Redox Biol. 2015 Aug;5:163-168
pubmed: 25965144
Biosci Rep. 2018 Nov 20;38(6):
pubmed: 30341250
J Pineal Res. 2016 Aug;61(1):52-68
pubmed: 26993080
J Clin Invest. 2009 May;119(5):1275-85
pubmed: 19349686
Am J Respir Crit Care Med. 2013 Mar 1;187(5):509-17
pubmed: 23348975
Cell Death Dis. 2019 Jul 8;10(7):524
pubmed: 31285425
Cardiovasc Drugs Ther. 2017 Feb;31(1):87-107
pubmed: 28190190
Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19500-5
pubmed: 18048346
Eur Urol. 2019 Sep;76(3):398-403
pubmed: 31080127
Kidney Dis (Basel). 2015 May;1(1):71-9
pubmed: 27536667
Cell. 2016 Feb 25;164(5):872-83
pubmed: 26919426
Cell Physiol Biochem. 2018;46(3):975-985
pubmed: 29680838
Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2293-2302
pubmed: 31100337
Front Immunol. 2018 Nov 12;9:2563
pubmed: 30483252
Proc Natl Acad Sci U S A. 2019 Nov 12;116(46):23332-23338
pubmed: 31653761
Nat Rev Mol Cell Biol. 2018 Jan 23;19(2):93-108
pubmed: 29358684
Kidney Int. 2016 Apr;89(4):779-91
pubmed: 26924060
Science. 2013 Apr 26;340(6131):471-5
pubmed: 23620051
Nat Commun. 2013;4:1982
pubmed: 23770887
Science. 2004 May 21;304(5674):1158-60
pubmed: 15087508
Chin Med J (Engl). 2019 Oct 5;132(19):2340-2347
pubmed: 31567378
Circulation. 2008 Jan 22;117(3):396-404
pubmed: 18178777
Autophagy. 2017 Jun 3;13(6):1080-1081
pubmed: 28323531
Nat Rev Nephrol. 2017 Oct;13(10):629-646
pubmed: 28804120
Intensive Care Med. 2017 Jun;43(6):855-866
pubmed: 28466146
Autophagy. 2013 Nov 1;9(11):1720-36
pubmed: 24091872
Am J Physiol Renal Physiol. 2013 Aug 15;305(4):F495-509
pubmed: 23698117
J Cell Biol. 2018 Aug 6;217(8):2743-2763
pubmed: 29848619
Theranostics. 2019 Feb 28;9(6):1698-1713
pubmed: 31037132
Antioxidants (Basel). 2019 Jun 14;8(6):
pubmed: 31197113
J Crit Care. 2013 Aug;28(4):389-96
pubmed: 23743540
EMBO J. 2018 Nov 2;37(21):
pubmed: 30237312
Pharmacol Res. 2018 Dec;138:43-56
pubmed: 30219582
Oxid Med Cell Longev. 2019 May 16;2019:7096912
pubmed: 31223426
Semin Nephrol. 2018 Mar;38(2):121-126
pubmed: 29602395
Cell Death Dis. 2019 Sep 12;10(9):677
pubmed: 31515472
J Am Soc Nephrol. 2018 Jan;29(1):194-206
pubmed: 29084809
Autophagy. 2018;14(5):880-897
pubmed: 29172924
Chin Med J (Engl). 2018 Nov 20;131(22):2769-2772
pubmed: 30425211
Protein Cell. 2017 Jan;8(1):25-38
pubmed: 27757847
Nature. 2015 Jun 18;522(7556):354-8
pubmed: 26040720
Nature. 2015 Aug 20;524(7565):309-314
pubmed: 26266977
Biochim Biophys Acta. 2013 Jan;1833(1):150-61
pubmed: 22580041
Antioxid Redox Signal. 2016 Jul 20;25(3):119-46
pubmed: 26906267
Oncotarget. 2017 Aug 3;8(61):102989-103003
pubmed: 29262539
Circ J. 2010 Oct;74(10):2216-24
pubmed: 20818133
Cell Death Dis. 2018 Nov 1;9(11):1113
pubmed: 30385753
J Intensive Care. 2016 Mar 23;4:17
pubmed: 27011788
Trends Cell Biol. 2015 Mar;25(3):158-70
pubmed: 25499735
J Am Soc Nephrol. 2017 May;28(5):1421-1436
pubmed: 27895157
Arch Toxicol. 2018 Jul;92(7):2245-2257
pubmed: 29860548
Nutrients. 2018 Oct 20;10(10):
pubmed: 30347790
Biomed Pharmacother. 2019 Jul;115:108914
pubmed: 31071510
Autophagy. 2019 Dec;15(12):2142-2162
pubmed: 31066324
Curr Top Microbiol Immunol. 2009;335:1-32
pubmed: 19802558
Autophagy. 2018;14(5):915-917
pubmed: 28614042
J Biol Chem. 1999 Jan 1;274(1):7-10
pubmed: 9867803
Nat Rev Nephrol. 2020 Feb;16(2):99-111
pubmed: 31673160
J Cell Physiol. 2019 Jun;234(6):8122-8133
pubmed: 30417391
J Agric Food Chem. 2019 Sep 11;67(36):10097-10106
pubmed: 31418272
Semin Nephrol. 2014 Jan;34(1):17-26
pubmed: 24485026