Utilization, effectiveness, and safety of tranexamic acid use in hip fracture surgery: A population-based study.
Blood transfusion
Complications
Hip fracture
Hospitalization cost
Tranexamic acid
Journal
Journal of orthopaedics
ISSN: 0972-978X
Titre abrégé: J Orthop
Pays: India
ID NLM: 101233220
Informations de publication
Date de publication:
Historique:
received:
20
01
2020
accepted:
25
01
2020
entrez:
7
2
2020
pubmed:
7
2
2020
medline:
7
2
2020
Statut:
epublish
Résumé
To assess the effect of tranexamic acid (TXA) use in hip fracture surgery. A retrospective cohort study was performed using the Premier Healthcare database. A propensity score matching approach was applied to assess associations between TXA use and blood transfusion, perioperative complications, length of stay (LOS), and hospitalization cost. In 153,169 patients, TXA use was associated with a 17% decrease in odds of blood transfusion, no increase in the risk of perioperative complications, 16% shorter LOS, and minimal effects on hospitalization cost. Our results are in support of a wider use of TXA in hip fracture surgery. Level III.
Identifiants
pubmed: 32025142
doi: 10.1016/j.jor.2020.01.040
pii: S0972-978X(20)30052-0
pmc: PMC6997115
doi:
Types de publication
Journal Article
Langues
eng
Pagination
167-172Informations de copyright
© 2020 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Each author certifies that he or she has no commercial associations (e.g., consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article.
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