Alterations of Several Serum Parameters Are Associated with Preeclampsia and May Be Potential Markers for the Assessment of PE Severity.


Journal

Disease markers
ISSN: 1875-8630
Titre abrégé: Dis Markers
Pays: United States
ID NLM: 8604127

Informations de publication

Date de publication:
2020
Historique:
received: 10 09 2019
revised: 21 11 2019
accepted: 31 12 2019
entrez: 7 2 2020
pubmed: 7 2 2020
medline: 30 9 2020
Statut: epublish

Résumé

The precise pathophysiological mechanisms of preeclampsia (PE) and preventative strategies remain unknown. Laboratory markers which can help in identifying PE patients from pregnant women and assessing the severity of PE during pregnancy are worthy to be explored. In this study, a retrospective case-control study was designed to assess whether the serum levels of albumin (ALB), total protein (TP), prealbumin (PA), alkaline phosphatase (ALP), lactic dehydrogenase (LDH), D-dimer, fibrinogen (Fbg), platelet (PLT) count, mean platelet volume (MPV), and platelet distribution width (PDW) can help in assessing PE and evaluate its severity. 256 pregnant women were enrolled and classified into 3 groups: mild preeclampsia (mPE,

Identifiants

pubmed: 32025276
doi: 10.1155/2020/7815214
pmc: PMC6983284
doi:

Substances chimiques

Biomarkers 0
Fibrin Fibrinogen Degradation Products 0
Prealbumin 0
fibrin fragment D 0
Fibrinogen 9001-32-5
L-Lactate Dehydrogenase EC 1.1.1.27
Alkaline Phosphatase EC 3.1.3.1

Types de publication

Journal Article Retracted Publication

Langues

eng

Sous-ensembles de citation

IM

Pagination

7815214

Commentaires et corrections

Type : RetractionIn

Informations de copyright

Copyright © 2020 Zhongliang Duan et al.

Déclaration de conflit d'intérêts

The authors declared no potential conflicts of interests with respect to the authorship and publication of this article.

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Auteurs

Zhongliang Duan (Z)

Department of Clinical Laboratory, Hospital of Obstetrics and Gynecology, Fudan University, Shanghai, China.

Cui Li (C)

Department of Clinical Laboratory, Hospital of Obstetrics and Gynecology, Fudan University, Shanghai, China.

Wing Ting Leung (WT)

Laboratory for Reproductive Immunology, Hospital & Institute of Obstetrics and Gynecology, Shanghai Medical College, Fudan University, Shanghai, China.
The Academy of Integrative Medicine, Fudan University, Shanghai, China.
Shanghai Key Laboratory of Female Reproductive Endocrine-related Diseases, Shanghai, China.

Jiangnan Wu (J)

Department of Clinical Epidemiology, Hospital of Obstetrics and Gynecology, Fudan University, Shanghai, China.

Mingyan Wang (M)

Department of Clinical Laboratory, Hospital of Obstetrics and Gynecology, Fudan University, Shanghai, China.

Chunmei Ying (C)

Department of Clinical Laboratory, Hospital of Obstetrics and Gynecology, Fudan University, Shanghai, China.

Ling Wang (L)

Laboratory for Reproductive Immunology, Hospital & Institute of Obstetrics and Gynecology, Shanghai Medical College, Fudan University, Shanghai, China.
The Academy of Integrative Medicine, Fudan University, Shanghai, China.
Shanghai Key Laboratory of Female Reproductive Endocrine-related Diseases, Shanghai, China.

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