Shigella flexneri: an emerging pathogen.


Journal

Folia microbiologica
ISSN: 1874-9356
Titre abrégé: Folia Microbiol (Praha)
Pays: United States
ID NLM: 0376757

Informations de publication

Date de publication:
Apr 2020
Historique:
received: 23 07 2019
accepted: 16 01 2020
pubmed: 7 2 2020
medline: 2 10 2020
entrez: 7 2 2020
Statut: ppublish

Résumé

Shigella flexneri is a leading etiologic agent of diarrhea in low socioeconomic countries. Notably, various serotypes in S. flexneri are reported from different regions of the world. The precise approximations of illness and death owing to shigellosis are missing in low socioeconomic countries, although it is widespread in different regions. The inadequate statistics available reveal S. flexneri to be a significant food and waterborne pathogen. All over the world, different antibiotic-resistant strains of S. flexneri serotypes have been emerged especially multidrug-resistant strains. Recently, increased resistance was observed in cephalosporins (3rd generation), azithromycin, and fluoroquinolones. There is a need for a continuous surveillance study on antibiotic resistance that will be helpful in the update of the antibiogram. The shigellosis burden can be reduced by adopting preventive measures like delivery of safe drinking water, suitable sanitation, and development of an effective and inexpensive multivalent vaccine. This review attempts to provide the recent findings of S. flexneri related to epidemiology and the emergence of multidrug resistance.

Identifiants

pubmed: 32026288
doi: 10.1007/s12223-020-00773-w
pii: 10.1007/s12223-020-00773-w
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

275-291

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Auteurs

Iqbal Nisa (I)

Department of Microbiology, Kohat University of Science and Technology, Kohat, Pakistan. n.nisa78@yahoo.com.

Muhammad Qasim (M)

Department of Microbiology, Kohat University of Science and Technology, Kohat, Pakistan.

Nusrat Yasin (N)

Department of Microbiology, Kohat University of Science and Technology, Kohat, Pakistan.

Rafi Ullah (R)

Bacteriology Laboratory Center of Microbiology and Bacteriology (CMB) Veterinary Research Institute, Peshawar, Pakistan.

Anwar Ali (A)

Bacteriology Laboratory Center of Microbiology and Bacteriology (CMB) Veterinary Research Institute, Peshawar, Pakistan.

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