Effect of Baseline Symptom Manifestations on Retention in Care and Treatment among HIV-Infected Patients in Nigeria.
Adolescent
Adult
Anti-Retroviral Agents
/ therapeutic use
Disease Management
Female
HIV Infections
/ drug therapy
Humans
Male
Middle Aged
Multivariate Analysis
Nigeria
/ epidemiology
Prevalence
Retention in Care
/ statistics & numerical data
Retrospective Studies
Symptom Assessment
Treatment Outcome
Young Adult
antiretroviral therapy
retention
symptoms
treatment outcomes
Journal
Journal of the International Association of Providers of AIDS Care
ISSN: 2325-9582
Titre abrégé: J Int Assoc Provid AIDS Care
Pays: United States
ID NLM: 101603896
Informations de publication
Date de publication:
Historique:
entrez:
7
2
2020
pubmed:
7
2
2020
medline:
20
5
2021
Statut:
ppublish
Résumé
Symptom management is an important component of HIV care. But symptom patterns and how they affect engagement with HIV care and treatment services have not been adequately explored in the era of increased HIV treatment scale-up. We investigated the relationship between symptom patterns among people living with HIV (PLHIV) and 12 months retention in care, within the context of other clinical and demographic characteristics. Retrospective cohort analysis of 5114 PLHIV receiving care within a large HIV treatment program in Nigeria. We assessed the prevalence and burden of baseline symptoms reported during routine clinic visits from January 2015 to December 2017. Multivariable regression was used to identify relationships between 12-month retention and symptom dimensions (prevalence and burden) while controlling for demographic and other clinical variables. Increasing symptom burden was associated with higher likelihood of retention at 12 months (adjusted odds ratio [aOR] = 1.19 [95% confidence interval, CI: 1.09-1.29];
Sections du résumé
BACKGROUND
Symptom management is an important component of HIV care. But symptom patterns and how they affect engagement with HIV care and treatment services have not been adequately explored in the era of increased HIV treatment scale-up. We investigated the relationship between symptom patterns among people living with HIV (PLHIV) and 12 months retention in care, within the context of other clinical and demographic characteristics.
METHODS
Retrospective cohort analysis of 5114 PLHIV receiving care within a large HIV treatment program in Nigeria. We assessed the prevalence and burden of baseline symptoms reported during routine clinic visits from January 2015 to December 2017. Multivariable regression was used to identify relationships between 12-month retention and symptom dimensions (prevalence and burden) while controlling for demographic and other clinical variables.
RESULTS
Increasing symptom burden was associated with higher likelihood of retention at 12 months (adjusted odds ratio [aOR] = 1.19 [95% confidence interval, CI: 1.09-1.29];
Identifiants
pubmed: 32027211
doi: 10.1177/2325958220903575
pmc: PMC7005974
doi:
Substances chimiques
Anti-Retroviral Agents
0
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
2325958220903575Subventions
Organisme : NIAID NIH HHS
ID : K23 AI106406
Pays : United States
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