Voltage dependent allosteric modulation of IPSCs by benzodiazepines.

Allosteric Regulation / drug effects Animals Benzodiazepines / metabolism Hippocampus / drug effects Induced Pluripotent Stem Cells / drug effects Membrane Potentials / drug effects Mice Midazolam / metabolism Patch-Clamp Techniques Pyramidal Cells / drug effects Receptors, GABA-A / drug effects Synapses / physiology Synaptic Transmission / physiology
GABA Hippocampal neurons Midazolam, Benzodiazepines Slice cultures

Journal

Brain research
ISSN: 1872-6240
Titre abrégé: Brain Res
Pays: Netherlands
ID NLM: 0045503

Informations de publication

Date de publication:
01 06 2020
Historique:
received: 21 06 2019
revised: 04 01 2020
accepted: 02 02 2020
pubmed: 7 2 2020
medline: 3 8 2021
entrez: 7 2 2020
Statut: ppublish

Résumé

GABA

Identifiants

DOI: 10.1016/j.brainres.2020.146699 PMID: 32027866 PMC: PMC8523021
pubmed: 32027866
pii: S0006-8993(20)30055-X
doi: 10.1016/j.brainres.2020.146699
pmc: PMC8523021
mid: NIHMS1746791
pii:
doi:

Substances chimiques

Receptors, GABA-A 0
Benzodiazepines 12794-10-4
Midazolam R60L0SM5BC

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

146699

Subventions

Organisme : NINDS NIH HHS
ID : R01 NS088479
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM008444
Pays : United States

Informations de copyright

Copyright © 2020. Published by Elsevier B.V.

Références

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Auteurs

Alexander Baez (A)

Medical Scientist Training Program (MSTP), Stony Brook University, Stony Brook, NY 11794, USA.

Trevor Van Brunt (T)

Department of Neurobiology & Behavior, Stony Brook University, Stony Brook, NY 11794, USA.

Gabrielle Moody (G)

Department of Molecular and Cellular Pharmacology, Stony Brook University, Stony Brook, NY 11794, USA.

Lonnie P Wollmuth (LP)

Department of Neurobiology & Behavior, Stony Brook University, Stony Brook, NY 11794, USA; Department of Biochemistry & Cell Biology, Stony Brook University, Stony Brook, NY 11794, USA; Center for Nervous System Disorders, Stony Brook University, Stony Brook, NY 11794-5230, USA.

Helen Hsieh (H)

Department of Surgery, Stony Brook Medicine, Stony Brook, NY 11794-8191, USA; Department of Pediatrics, Stony Brook Medicine, Stony Brook, NY 11794-8191, USA. Electronic address: helen.hsieh@stonybrookmedicine.edu.

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Classifications MeSH

questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Régulation allostérique › Voltage dependent allosteric modulation of...
questionsmedicales.fr › Eucaryotes › Animaux › Voltage dependent allosteric modulation of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzazépines › Benzodiazépines › Voltage dependent allosteric modulation of...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Télencéphale › Cerveau › Cortex cérébral › Hippocampe › Voltage dependent allosteric modulation of...
questionsmedicales.fr › Cellules › Cellules souches › Cellules souches pluripotentes › Cellules souches pluripotentes induites › Voltage dependent allosteric modulation of...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Potentiels de membrane › Voltage dependent allosteric modulation of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Voltage dependent allosteric modulation of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzazépines › Benzodiazépines › Midazolam › Voltage dependent allosteric modulation of...
questionsmedicales.fr › Techniques d'investigation › Techniques cytologiques › Techniques de patch-clamp › Voltage dependent allosteric modulation of...
questionsmedicales.fr › Cellules › Neurones › Cellules pyramidales › Voltage dependent allosteric modulation of...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs aux acides aminés › Récepteurs GABA › Récepteurs GABA-A › Voltage dependent allosteric modulation of...
questionsmedicales.fr › Cellules › Structures cellulaires › Membrane cellulaire › Structures de la membrane cellulaire › Jonctions intercellulaires › Synapses › Voltage dependent allosteric modulation of...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Transmission synaptique › Voltage dependent allosteric modulation of...