"Two-Birds-One-Stone" Approach for Treating an Infant with Chiari I Malformation and Hydrocephalus: Is Cerebrospinal Fluid Diversion as Sole Treatment Enough?


Journal

World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275

Informations de publication

Date de publication:
05 2020
Historique:
received: 24 11 2019
revised: 23 01 2020
accepted: 24 01 2020
pubmed: 7 2 2020
medline: 22 7 2020
entrez: 7 2 2020
Statut: ppublish

Résumé

Chiari I malformation (CIM) is a disorder characterized by caudal displacement of the cerebellar tonsils below the foramen magnum. It is often associated with syringomyelia and occasionally with hydrocephalus. CIM is commonly treated by posterior fossa decompression with or without removal of the posterior arch of C1 and duraplasty, but the treatment for infants with symptomatic CIM is not well established. We present a case of symptomatic CIM in an infant that was successfully treated with a ventriculoperitoneal shunt (VPS) and discuss the importance of the pathophysiology in management decisions. A 6-month-old male with a CIM and a cervicothoracic syrinx presented with stridor, lower cranial nerve dysfunction, and increased tone that worsened with crying. Magnetic resonance imaging studies revealed cerebellar tonsillar displacement extending to the level of C3-C4 with a syrinx extending from C4 to T4. In addition, there was compression of the cervicomedullary junction, fourth ventricular outflow obstruction, and obstructive hydrocephalus. The decision was made to place a ventriculoperitoneal shunt (VPS) instead of performing decompressive surgery as the initial treatment intervention. The infant had significant symptomatic relief at 6-, 9-, and 12-month follow-ups. Postoperative magnetic resonance imaging at 6-month follow-up revealed resolution of the syrinx and ventriculomegaly and ascent of the cerebellar tonsils. Ventriculoperitoneal shunting alone was successfully used to treat an infant with concurrent CIM, syrinx, and hydrocephalus. This case underscores not only the importance of hydrocephalus as the pathogenesis of CIM in some cases but also the possibility of avoiding the morbidity of decompressive surgery in infants.

Sections du résumé

BACKGROUND
Chiari I malformation (CIM) is a disorder characterized by caudal displacement of the cerebellar tonsils below the foramen magnum. It is often associated with syringomyelia and occasionally with hydrocephalus. CIM is commonly treated by posterior fossa decompression with or without removal of the posterior arch of C1 and duraplasty, but the treatment for infants with symptomatic CIM is not well established. We present a case of symptomatic CIM in an infant that was successfully treated with a ventriculoperitoneal shunt (VPS) and discuss the importance of the pathophysiology in management decisions.
CASE DESCRIPTION
A 6-month-old male with a CIM and a cervicothoracic syrinx presented with stridor, lower cranial nerve dysfunction, and increased tone that worsened with crying. Magnetic resonance imaging studies revealed cerebellar tonsillar displacement extending to the level of C3-C4 with a syrinx extending from C4 to T4. In addition, there was compression of the cervicomedullary junction, fourth ventricular outflow obstruction, and obstructive hydrocephalus. The decision was made to place a ventriculoperitoneal shunt (VPS) instead of performing decompressive surgery as the initial treatment intervention. The infant had significant symptomatic relief at 6-, 9-, and 12-month follow-ups. Postoperative magnetic resonance imaging at 6-month follow-up revealed resolution of the syrinx and ventriculomegaly and ascent of the cerebellar tonsils.
CONCLUSIONS
Ventriculoperitoneal shunting alone was successfully used to treat an infant with concurrent CIM, syrinx, and hydrocephalus. This case underscores not only the importance of hydrocephalus as the pathogenesis of CIM in some cases but also the possibility of avoiding the morbidity of decompressive surgery in infants.

Identifiants

pubmed: 32028005
pii: S1878-8750(20)30206-0
doi: 10.1016/j.wneu.2020.01.188
pii:
doi:

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

174-177

Commentaires et corrections

Type : CommentIn
Type : CommentIn

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Mansour Mathkour (M)

Department of Neurosurgery, Ochsner Clinic Foundation, New Orleans, Louisiana, USA; Department of NeurosurgeryTulane Medical Center, New Orleans, Louisiana, USA. Electronic address: mathkour.mansour@gmail.com.

Joseph R Keen (JR)

Department of Neurosurgery, Ochsner Clinic Foundation, New Orleans, Louisiana, USA.

Brendan Huang (B)

Department of NeurosurgeryTulane Medical Center, New Orleans, Louisiana, USA.

Cassidy Werner (C)

Department of NeurosurgeryTulane Medical Center, New Orleans, Louisiana, USA.

Tyler Scullen (T)

Department of Neurosurgery, Ochsner Clinic Foundation, New Orleans, Louisiana, USA; Department of NeurosurgeryTulane Medical Center, New Orleans, Louisiana, USA.

Juanita Garces (J)

Department of Neurosurgery, Ochsner Clinic Foundation, New Orleans, Louisiana, USA; Department of NeurosurgeryTulane Medical Center, New Orleans, Louisiana, USA.

Matthew Skovgard (M)

Department of NeurosurgeryTulane Medical Center, New Orleans, Louisiana, USA.

Joe Iwanaga (J)

Department of Neurosurgery, Ochsner Clinic Foundation, New Orleans, Louisiana, USA; Department of NeurosurgeryTulane Medical Center, New Orleans, Louisiana, USA; Department of Structural & Cellular Biology, Tulane University School of Medicine, New Orleans, Louisiana, USA.

R Shane Tubbs (RS)

Department of Neurosurgery, Ochsner Clinic Foundation, New Orleans, Louisiana, USA; Department of NeurosurgeryTulane Medical Center, New Orleans, Louisiana, USA; Department of Structural & Cellular Biology, Tulane University School of Medicine, New Orleans, Louisiana, USA.

Aaron Dumont (A)

Department of Neurosurgery, Ochsner Clinic Foundation, New Orleans, Louisiana, USA; Department of NeurosurgeryTulane Medical Center, New Orleans, Louisiana, USA.

Erin Biro (E)

Department of Neurosurgery, Ochsner Clinic Foundation, New Orleans, Louisiana, USA.

Cuong J Bui (CJ)

Department of Neurosurgery, Ochsner Clinic Foundation, New Orleans, Louisiana, USA.

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