Bortezomib with standard chemotherapy for children with acute myeloid leukemia does not improve treatment outcomes: a report from the Children's Oncology Group.
Journal
Haematologica
ISSN: 1592-8721
Titre abrégé: Haematologica
Pays: Italy
ID NLM: 0417435
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
received:
07
03
2019
accepted:
05
02
2020
pubmed:
8
2
2020
medline:
28
4
2021
entrez:
8
2
2020
Statut:
ppublish
Résumé
New therapeutic strategies are needed for pediatric acute myeloid leukemia (AML) to reduce disease recurrence and treatment-related morbidity. The Children's Oncology Group Phase III AAML1031 trial tested whether the addition of bortezomib to standard chemotherapy improves survival in pediatric patients with newly diagnosed AML. AAML1031 randomized patients younger than 30 years of age with
Identifiants
pubmed: 32029509
pii: haematol.2019.220962
doi: 10.3324/haematol.2019.220962
pmc: PMC7327649
doi:
Substances chimiques
Cytarabine
04079A1RDZ
Bortezomib
69G8BD63PP
Banques de données
ClinicalTrials.gov
['NCT01371981']
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
1879-1886Subventions
Organisme : NCI NIH HHS
ID : U10 CA180886
Pays : United States
Organisme : NCI NIH HHS
ID : U10 CA180899
Pays : United States
Informations de copyright
Copyright© 2020 Ferrata Storti Foundation.
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