HBV vaccination status among healthcare workers: A cross-sectional study.

Vaccination blood-borne viruses epidemiology

Journal

Journal of infection prevention
ISSN: 1757-1774
Titre abrégé: J Infect Prev
Pays: England
ID NLM: 101469725

Informations de publication

Date de publication:
Jan 2020
Historique:
received: 06 11 2018
accepted: 28 07 2019
entrez: 8 2 2020
pubmed: 8 2 2020
medline: 8 2 2020
Statut: ppublish

Résumé

The development of a vaccine against hepatitis B virus (HBV) is one of the improvements in strategy prevention during the last decades. To evaluate HBV-related vaccine status in healthcare workers (HCW) exposed to biological risk. The serum markers for HBV were collected from HCWs in two tertiary care hospitals in Naples (Italy). Multivariate statistical analysis was then performed to identify associated factors linked to the long-term immunogenicity of the HCWs. All HBV vaccinated individuals were screened for whole marker patterns; all were HBsAg/anti-HBc negative. Of individuals, 20% had an anti-HB antibody titre < 10 IU/L. Multivariate statistical analysis highlighted that women were more protected than men (73.6% vs. 26.4%, Our data support the evidence of a strong immunogenicity against HBV, assessed through the circulating antibody titre, when prophylactic vaccination is conducted in non-infantile age, particularly for women. The outcome of the study supports the central role of occupational physicians within the hospital districts in terms of primary prevention and maximum protection of HCWs.

Identifiants

pubmed: 32030100
doi: 10.1177/1757177419873043
pii: 10.1177_1757177419873043
pmc: PMC6978564
doi:

Types de publication

Journal Article

Langues

eng

Pagination

23-27

Informations de copyright

© The Author(s) 2019.

Déclaration de conflit d'intérêts

Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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Auteurs

Elpidio Maria Garzillo (EM)

Department of Experimental Medicine- University of Campania L. Vanvitelli, Naples, Italy.

Antonio Arnese (A)

Department of Experimental Medicine- University of Campania L. Vanvitelli, Naples, Italy.

Nicola Coppola (N)

Department of Mental and Physical Health and Preventive Medicine, University of Campania L. Vanvitelli, Naples, Italy.

AnnaRita Corvino (A)

Department of Experimental Medicine- University of Campania L. Vanvitelli, Naples, Italy.

Daniela Feola (D)

Department of Experimental Medicine- University of Campania L. Vanvitelli, Naples, Italy.

Maria Grazia Lourdes Monaco (MGL)

Integrated University Hospital of Verona, Occupational Medicine Unit Verona, Veneto, Italy.

Giuseppe Signoriello (G)

Department of Mental and Physical Health and Preventive Medicine, University of Campania L. Vanvitelli, Naples, Italy.

Luigi Tonino Marsella (LT)

Departiment of Biomedicine and Prevention, Università di Roma Tor Vergata, Rome, Italy.

Paola Arena (P)

Department of Experimental Medicine- University of Campania L. Vanvitelli, Naples, Italy.

Monica Lamberti (M)

Department of Experimental Medicine- University of Campania L. Vanvitelli, Naples, Italy.

Classifications MeSH