Interpersonal Risk Factors for Suicide in Cocaine Dependence: Association with Self-Esteem, Personality Traits, and Childhood Abuse.


Journal

Suicide & life-threatening behavior
ISSN: 1943-278X
Titre abrégé: Suicide Life Threat Behav
Pays: England
ID NLM: 7608054

Informations de publication

Date de publication:
08 2020
Historique:
received: 17 05 2019
accepted: 10 01 2020
pubmed: 8 2 2020
medline: 28 4 2021
entrez: 8 2 2020
Statut: ppublish

Résumé

Studies have linked cocaine dependence to suicidality. According to the Interpersonal Theory of Suicide, suicidal behavior becomes likely with the simultaneous presence of perceived burdensomeness (PB), lack of (or thwarted) belongingness (TB), and acquired fearlessness about death (FAD). Here, we examined personality and other variables, including depression, self-esteem, childhood abuse, and substance use, as predictors of these risk factors in cocaine-dependent individuals (CDs). Seventy CDs and 70 healthy controls (HCs) participated. We examined group differences in a group-by-sex analysis of variance and identified predictors of PB, TB, and FAD in stepwise regressions. CDs exhibited elevated PB and TB but not FAD, compared to HCs. CDs also exhibited elevated harm avoidance, novelty seeking, depression, and lower self-esteem and reward dependence. Females reported elevated sexual abuse, harm avoidance, reward dependence, depression, but lower FAD, relative to males, among CDs and HCs. Among CDs, PB was predicted by lower self-esteem and greater emotional abuse; TB was predicted by lower self-esteem and reward dependence, as well as greater emotional and sexual abuse; and FAD was predicted by lower harm avoidance and greater physical abuse. Interventions targeting suicidality in cocaine dependence should take into consideration self-esteem, personality traits, and childhood abuse.

Identifiants

pubmed: 32030810
doi: 10.1111/sltb.12621
pmc: PMC7518050
mid: NIHMS1627236
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

867-883

Subventions

Organisme : NIDA NIH HHS
ID : R21 DA044749
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA023248
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007205
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM136651
Pays : United States

Informations de copyright

© 2020 The American Association of Suicidology.

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Auteurs

Simon Zhornitsky (S)

Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.

Thang M Le (TM)

Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.

Isha Dhingra (I)

Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.

Brendan D Adkinson (BD)

Interdepartmental Neuroscience Program, Yale University School of Medicine, New Haven, Connecticut.

Stephane Potvin (S)

Centre de recherche de l'Institut, Universitaire en Santé Mentale de Montréal, Montreal, QC, Canada.
Department of Psychiatry, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.

Chiang-Shan R Li (CR)

Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
Interdepartmental Neuroscience Program, Yale University School of Medicine, New Haven, Connecticut.
Department of Neuroscience, Yale University School of Medicine, New Haven, Connecticut.

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