Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective.

Animals Antineoplastic Agents / chemistry Enzyme Inhibitors / chemistry Gene Regulatory Networks / drug effects Humans Neoplasms / drug therapy Protein Structure, Secondary Sarcoplasmic Reticulum Calcium-Transporting ATPases / antagonists & inhibitors

Journal

Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531

Informations de publication

Date de publication:
12 03 2020
Historique:
pubmed: 8 2 2020
medline: 20 8 2020
entrez: 8 2 2020
Statut: ppublish

Résumé

The sarco/endoplasmic reticulum calcium ATPase (SERCA), which plays a key role in the maintenance of Ca

Identifiants

DOI: 10.1021/acs.jmedchem.9b01509 PMID: 32030976
pubmed: 32030976
doi: 10.1021/acs.jmedchem.9b01509
doi:

Substances chimiques

Antineoplastic Agents 0
Enzyme Inhibitors 0
Sarcoplasmic Reticulum Calcium-Transporting ATPases EC 3.6.3.8

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1937-1963

Auteurs

Lucie Peterková (L)

Department of Biochemistry and Microbiology, University of Chemistry and Technology Prague, Technická 5, 166 28, Prague 6, Czech Republic.

Eva Kmoníčková (E)

Faculty of Medicine in Pilsen, Charles University, Alej Svobody 76, 323 00 Pilsen, Czech Republic.

Tomáš Ruml (T)

Department of Biochemistry and Microbiology, University of Chemistry and Technology Prague, Technická 5, 166 28, Prague 6, Czech Republic.

Silvie Rimpelová (S)

Department of Biochemistry and Microbiology, University of Chemistry and Technology Prague, Technická 5, 166 28, Prague 6, Czech Republic.
Faculty of Medicine in Pilsen, Charles University, Alej Svobody 76, 323 00 Pilsen, Czech Republic.
ORCID: 0000-0002-3008-1396

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Sarco/Endoplasmic Reticulum Calcium ATPase...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Sarco/Endoplasmic Reticulum Calcium ATPase...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Sarco/Endoplasmic Reticulum Calcium ATPase...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Séquences d'acides nucléiques régulatrices › Réseaux de régulation génique › Sarco/Endoplasmic Reticulum Calcium ATPase...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Sarco/Endoplasmic Reticulum Calcium ATPase...
questionsmedicales.fr › Tumeurs › Sarco/Endoplasmic Reticulum Calcium ATPase...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure secondaire des protéines › Sarco/Endoplasmic Reticulum Calcium ATPase...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › P-type ATPases › Calcium-Transporting ATPases › Sarcoplasmic Reticulum Calcium-Transporting ATPases › Sarco/Endoplasmic Reticulum Calcium ATPase...