Infections and the development of childhood acute lymphoblastic leukemia: a population-based study.
Journal
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)
ISSN: 1473-5709
Titre abrégé: Eur J Cancer Prev
Pays: England
ID NLM: 9300837
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
pubmed:
8
2
2020
medline:
31
8
2021
entrez:
8
2
2020
Statut:
ppublish
Résumé
An infectious trigger for childhood acute lymphoblastic leukemia is hypothesized and we assessed the association between the rate, type, and critical exposure period for infections and the development of acute lymphoblastic leukemia. We conducted a matched case-control study using administrative databases to evaluate the association between the rate of infections and childhood acute lymphoblastic leukemia diagnosed between the ages of 2-14 years from Ontario, Canada and we used a validated approach to measure infections. In 1600 cases of acute lymphoblastic leukemia, and 16 000 matched cancer-free controls aged 2-14 years, having >2 infections/year increased the odds of childhood acute lymphoblastic leukemia by 43% (odds ratio = 1.43, 95% confidence interval 1.13-1.81) compared to children with ≤0.25 infections/year. Having >2 respiratory infections/year increased odds of acute lymphoblastic leukemia by 28% (odds ratio =1.28, 95% confidence interval 1.05-1.57) compared to children with ≤0.25 respiratory infections/year. Having an invasive infection increased the odds of acute lymphoblastic leukemia by 72% (odds ratio =1.72, 95% confidence interval 1.31-2.26). Having an infection between the age of 1-1.5 years increased the odds of acute lymphoblastic leukemia by 20% (odds ratio = 1.20, 95% confidence interval 1.04-1.39). Having more infections increased the odds of developing childhood acute lymphoblastic leukemia and having an infection between the ages of 1-1.5 years increased the odds of childhood acute lymphoblastic leukemia.
Identifiants
pubmed: 32032155
doi: 10.1097/CEJ.0000000000000564
pii: 00008469-202011000-00010
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
538-545Subventions
Organisme : CIHR
Pays : Canada
Commentaires et corrections
Type : CommentIn
Références
Ajrouche R, Rudant J, Orsi L, Petit A, Baruchel A, Lambilliotte A, et al. Childhood acute lymphoblastic leukaemia and indicators of early immune stimulation: the Estelle study (SFCE). Br J Cancer. 2015; 112:1017–1026
Amitay EL, Keinan-Boker L. Breastfeeding and childhood leukemia incidence: a meta-analysis and systematic review. JAMA pediatrics. 2015; 169:e151025
Baade PD, Youlden DR, Valery PC, Hassall T, Ward L, Green AC, Aitken JF. Trends in incidence of childhood cancer in Australia, 1983-2006. Br J Cancer. 2010; 102:620–626
Bruijnzeels MA, Foets M, van der Wouden JC, van den Heuvel WJ, Prins A. Everyday symptoms in childhood: occurrence and general practitioner consultation rates. Br J Gen Pract. 1998; 48:880–884
Chang JS, Tsai CR, Tsai YW, Wiemels JL. Medically diagnosed infections and risk of childhood leukaemia: a population-based case-control study. Int J Epidemiol. 2012; 41:1050–1059
Chang JS, Zhou M, Buffler PA, Chokkalingam AP, Metayer C, Wiemels JL. Profound deficit of IL10 at birth in children who develop childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev. 2011; 20:1736–1740
Crouch S, Lightfoot T, Simpson J, Smith A, Ansell P, Roman E. Infectious illness in children subsequently diagnosed with acute lymphoblastic leukemia: modeling the trends from birth to diagnosis. Am J Epidemiol. 2012; 176:402–408
Ding S, Wang X, Chen W, Fang Y, Liu B, Liu Y, et al. Decreased Interleukin-10 responses in children with severe Mycoplasmapneumoniae Pneumonia. Plos One. 2016; 11:e0146397
Dores GM, Devesa SS, Curtis RE, Linet MS, Morton LM. Acute leukemia incidence and patient survival among children and adults in the united states, 2001-2007. Blood. 2012; 119:34–43
du Plessis V, Beshiri R, Bollman RD, Clemenson H. Agriculture and Rural Working Paper Series. Definitions of “Rural”. 2002, Ottawa, Canada: Statistics Canada
Fendrick AM, Monto AS, Nightengale B, Sarnes M. The economic burden of non-influenza-related viral respiratory tract infection in the united states. Arch Intern Med. 2003; 163:487–494
Greaves M. Infection, immune responses and the aetiology of childhood leukaemia. Nat Rev Cancer. 2006; 6:193–203
Greaves MF, Maia AT, Wiemels JL, Ford AM. Leukemia in twins: lessons in natural history. Blood. 2003; 102:2321–2333
Greenberg ML, Barr RD, DiMonte B, McLaughlin E, Greenberg C. Childhood cancer registries in Ontario, Canada: lessons learned from a comparison of two registries. Int J Cancer. 2003; 105:88–91
Hoebee B, Bont L, Rietveld E, van Oosten M, Hodemaekers HM, Nagelkerke NJ, et al. Influence of promoter variants of interleukin-10, interleukin-9, and tumor necrosis factor-alpha genes on respiratory syncytial virus bronchiolitis. J Infect Dis. 2004; 189:239–247
Holme CO. Incidence and prevalence of non-specific symptoms and behavioural changes in infants under the age of two years. Br J Gen Pract. 1995; 45:65–69
Hubbard AK, Spector LG, Fortuna G, Marcotte EL, Poynter JN. Trends in international incidence of pediatric cancers in children under 5 years of age: 1988-2012. JNCI Cancer Spectr. 2019; 3:pkz007
Hwee J, Tait C, Sung L, Kwong JC, Sutradhar R, Pole JD. A systematic review and meta-analysis of the association between childhood infections and the risk of childhood acute lymphoblastic leukaemia. Br J Cancer. 2018; 118:127–137
Hwee J, Sung L, Kwong JC, Sutradhar R, Tu K, Pole JD. Use of physician billing claims to identify infections in children. PLoS One. 2018; 13:e0207468
Johnston B, Conly J. The changing face of Canadian immigration: implications for infectious diseases. Can J Infect Dis Med Microbiol. 2008; 19:270–272
Jourdan-Da Silva N, Perel Y, Mechinaud F, Plouvier E, Gandemer V, Lutz P, et al. Infectious diseases in the first year of life, perinatal characteristics and childhood acute leukaemia. Br J Cancer. 2004; 90:139–145
Kinlen L. Evidence for an infective cause of childhood leukaemia: comparison of a Scottish new town with nuclear reprocessing sites in Britain. Lancet. 1988; 2:1323–1327
Kleinbaum DG, Klein M. Logistic Regression: A Self-Learning Text. 2010, New York: Springer-Verlag
Kwong JC, Ratnasingham S, Campitelli MA, Daneman N, Deeks SL, Manuel DG, et al. The impact of infection on population health: results of the Ontario burden of infectious diseases study. PLoS One. 2012; 7:e44103
Matheson FI, Dunn JR, Smith KL, Moineddin R, Glazier RH. Development of the Canadian marginalization index: a new tool for the study of inequality. Can J Public Health. 2012; 103:S12–S16
McKinney PA, Alexander FE, Nicholson C, Cartwright RA, Carrette J. Mothers’ reports of childhood vaccinations and infections and their concordance with general practitioner records. J Public Health Med. 1991; 13:13–22
Monto AS, Sullivan KM. Acute respiratory illness in the community. Frequency of illness and the agents involved. Epidemiol Infect. 1993; 110:145–160
Nelson W. Recurrent Events Data Analysis for Product Repairs, Disease Recurrences, and Other Applications. 2003, Schenectady, New York, American Statistical Association and the Society for Industrial and Applied Mathematics
Perrillat F, Clavel J, Auclerc MF, Baruchel A, Leverger G, Nelken B, et al. Day-care, early common infections and childhood acute leukaemia: a multicentre French case-control study. Br J Cancer. 2002; 86:1064–1069
Riley AW, Finney JW, Mellits ED, Starfield B, Kidwell S, Quaskey S, et al. Determinants of children’s health care use: an investigation of psychosocial factors. Med Care. 1993; 31:767–783
Roizen NJ, Patterson D. Down’s syndrome. Lancet. 2003; 361:1281–1289
Roman E, Simpson J, Ansell P, Kinsey S, Mitchell CD, McKinney PA, et al.; United Kingdom Childhood Cancer Study Investigators. Childhood acute lymphoblastic leukemia and infections in the first year of life: a report from the United Kingdom childhood cancer study. Am J Epidemiol. 2007; 165:496–504
Rudant J, Orsi L, Menegaux F, Petit A, Baruchel A, Bertrand Y, et al. Childhood acute leukemia, early common infections, and allergy: the ESCALE study. Am J Epidemiol. 2010; 172:1015–1027
Siegel DA, Henley SJ, Li J, Pollack LA, Van Dyne EA, White A. Rates and trends of pediatric acute lymphoblastic leukemia - United States, 2001-2014. MMWR Morb Mortal Wkly Rep. 2017; 66:950–954
Simpson J, Smith A, Ansell P, Roman E. Childhood leukaemia and infectious exposure: a report from the United Kingdom childhood cancer study (UKCCS). Eur J Cancer. 2007; 43:2396–2403
Sinha M. Spotlight on Canadians: Results from the General Social Survey. Child care in Canada. Analytic Paper. 2014, Ottawa: Statistics Canada
Stiller CA. Epidemiology and genetics of childhood cancer. Oncogene. 2004; 23:6429–6444
Urayama KY, Buffler PA, Gallagher ER, Ayoob JM, Ma X. A meta-analysis of the association between day-care attendance and childhood acute lymphoblastic leukaemia. Int J Epidemiol. 2010; 39:718–732
VanderWeele TJ, Ding P. Sensitivity analysis in observational research: introducing the E-value. Ann Intern Med. 2017; 167:268–274
Wiemels J. Perspectives on the causes of childhood leukemia. Chem Biol Interact. 2012; 196:59–67
Wilson A, Chiu YM, Hsu HL, Wright RO, Wright RJ, Coull BA. Potential for bias when estimating critical windows for air pollution in children’s health. Am J Epidemiol. 2017; 186:1281–1289
Xie L, Onysko J, Morrison H. Childhood cancer incidence in Canada: demographic and geographic variation of temporal trends (1992-2010). Health Promot Chronic Dis Prev Can. 2018; 38:79–115
Zhang G, Rowe J, Kusel M, Bosco A, McKenna K, de Klerk N, et al. Interleukin-10/interleukin-5 responses at birth predict risk for respiratory infections in children with atopic family history. Am J Respir Crit Care Med. 2009; 179:205–211