Health effects associated with short-term exposure to hydrogen sulfide from geothermal power plants: a case-crossover study in the geothermal areas in Tuscany.


Journal

International archives of occupational and environmental health
ISSN: 1432-1246
Titre abrégé: Int Arch Occup Environ Health
Pays: Germany
ID NLM: 7512134

Informations de publication

Date de publication:
08 2020
Historique:
received: 18 05 2019
accepted: 28 01 2020
pubmed: 9 2 2020
medline: 25 3 2021
entrez: 9 2 2020
Statut: ppublish

Résumé

Thirty-four geothermal power plants for the production of electricity are currently active in the geothermal areas in Tuscany. The present study aimed to investigate the association between short-term exposure to hydrogen sulfide (H This study used individual data on non-accidental, cardiovascular and respiratory mortality, urgent hospital admissions (HA) and emergency department (ED) visits for cardiorespiratory diseases occurring from 2000 to 2017. All cases were georeferenced and matched to daily H A total of 8054 deaths, 30,527 HA and 15,263 ED visits occurred. Mortality for non-accidental (OR = 1.11, 90% CI 1.02-1.22) and cardiovascular causes (OR = 1.22, 90% CI 1.03-1.44) were associated with an increase of 10 µg/m In this case-crossover study in the Tuscan geothermal areas, short-term exposure to H

Identifiants

pubmed: 32034472
doi: 10.1007/s00420-020-01522-9
pii: 10.1007/s00420-020-01522-9
doi:

Substances chimiques

Air Pollutants 0
Hydrogen Sulfide YY9FVM7NSN

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

669-682

Subventions

Organisme : Regione Toscana
ID : Resolution N. 973
Pays : International

Références

Agency for Toxic Substances and Disease Registry (ATSDR) (2006) Toxicological profile for Hydrogen Sulphide. ATSDR, Atlanta
Andreadou I, Iliodromitis EK, Rassaf T, Schulz R, Papapetropoulos A, Ferdinandy P (2015) The role of gasotransmitters NO, H
doi: 10.1111/bph.12811
Baccini M, Biggeri A, Lagazio C, Lertxundi A, Saez M (2007) Parametric and semi-parametric approaches in the analysis of short-term effects of air pollution on health. Comput Stat Data Anal 51:4324–4336
doi: 10.1016/j.csda.2006.05.026
Barbier E, Santoprete G (1993) L’energia geotermica Una fonte di energia all’interno della terra. Giappichelli Editore, Torino
Bates MN, Garrett N, Graham B, Read D (1997) Air pollution and mortality in the Rotorua geothermal area. Aust N Z J Public Health 21:581–586
doi: 10.1111/j.1467-842X.1997.tb01759.x
Bates MN, Garrett N, Graham B, Read D (1998) Cancer incidence, morbidity and geothermal air pollution in Rotorua. N Z Int J Epidemiol 27:10–14
doi: 10.1093/ije/27.1.10
Bates MN, Garrett N, Shoemack P (2002) Investigation of health effects of hydrogen sulfide from a geothermal source. Arch Environ Health 57:405–411. https://doi.org/10.1080/00039890209601428
doi: 10.1080/00039890209601428
Bates MN, Garret N, Crane J, Balmes JR (2013) Associations of ambient hydrogen sulfide exposure with self-reported asthma and asthma symptoms. Environ Res 122:81–87. https://doi.org/10.1016/j.envres.2013.02.002
doi: 10.1016/j.envres.2013.02.002
Bates MN, Crane J, Balmes JR, Garrett N (2015) Investigation of hydrogen sulphide exposure and lung function, asthma and chronic obstructive pulmonary disease in a geothermal area of New Zealand. PLoS ONE 10:e0122062. https://doi.org/10.1371/journal.pone.0122062
doi: 10.1371/journal.pone.0122062
Bates MN, Bailey IL, Di Martino RB, Pope K, Crane J, Garrett N (2017) Lens opacity and hydrogen sulfide in a New Zealand geothermal area. Optom Vis Sci 94:487–495. https://doi.org/10.1097/OPX.0000000000001049
doi: 10.1097/OPX.0000000000001049
Bateson TF, Schwartz J (1999) Control for seasonal variation and time trend in case-crossover studies of acute effects of environmental exposures. Epidemiology 10:539–544
doi: 10.1097/00001648-199909000-00013
Biggeri A, Baccini M, Accetta G, Bellini A, Grechi D, on behalf of MISA group (2003) Quality assessment of air pollutants concentration in epidemiologic time series on short-term effects of pollution on health. Epidemiol Prev 27:365–375
Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310
doi: 10.1016/S0140-6736(86)90837-8
Bustaffa E, Minichilli F, Nuvolone D, Voller F, Cipriani F, Bianchi F (2017) Mortality of populations residing in geothermal areas of Tuscany during the period 2003–2012. Ann Ist Super Sanita 53:108–117. https://doi.org/10.4415/ANN_17_02_06
doi: 10.4415/ANN_17_02_06
Campagna D, Kathman SJ, Pierson R, Inserra SG, Phifer BL, Middleton DC, Zarus GM, White MC (2004) Ambient hydrogen sulfide, total reduced sulfur, and hospital visits for respiratory diseases in northeast Nebraska, 1998–2000. J Expo Anal Environ Epidemiol 14:180–187
doi: 10.1038/sj.jea.7500313
Carlsen HK, Zoëga H, Valdimarsdóttir U, Gíslason T, Hrafnkelsson B (2012) Hydrogen sulfide and particle matter levels associated with increased dispensing of anti-asthma drugs in Iceland's capital. Environ Res 113:33–39. https://doi.org/10.1016/j.envres.2011.10.010
doi: 10.1016/j.envres.2011.10.010
Chiusolo M, Cadum E, Stafoggia M (2011) Short-term effects of nitrogen dioxide on mortality and susceptibility factors in 10 Italian cities: The EpiAir Study. Environ Health Perspect 119(9):1233–1238. https://doi.org/10.1289/ehp.1002904
doi: 10.1289/ehp.1002904
Dickson MH, Fanelli M (2003) Geothermal energy utilization and technology. Earthscan, London
Dominici F, Peng RD, Bell ML, Pham L, McDermott A, Zeger SL, Samet JM (2006) Fine particulate air pollution and hospital admission for cardiovascular and respiratory diseases. JAMA 295(10):1127–1134
doi: 10.1001/jama.295.10.1127
Dongó E, Hornyák I, Benko Z, Kiss L (2011) The cardioprotective potential of hydrogen sulfide in myocardial ischemia/reperfusion injury (review). Acta Physiol Hung 98:369–381. https://doi.org/10.1556/APhysiol.98.2011.4.1
doi: 10.1556/APhysiol.98.2011.4.1
Finnbjornsdottir RG, Oudin A, Elvarsson BT, Gislason T, Rafnsson V (2015) Hydrogen sulfide and traffic-related air pollutants in association with increased mortality: a case-crossover study in Reykjavik. Iceland. BMJ Open 5(4):e007272. https://doi.org/10.1136/bmjopen-2014-007272
doi: 10.1136/bmjopen-2014-007272
Finnbjornsdottir RG, Carlsen HK, Thorsteinsson T, Oudin A, Lund SH, Gislason T, Rafnsson V (2016) Association between Daily hydrogen sulfide exposure and incidence of emergency hospital visits: a population-based study. PLoS ONE 11(5):e0154946. https://doi.org/10.1371/journal.pone.0154946
doi: 10.1371/journal.pone.0154946
Greenland S (1996) Confounding and exposure trends in case-crossover and case-time-control designs. Epidemiology 7(3):231–239
doi: 10.1097/00001648-199605000-00003
Jaakkola JJ, Paunio M, Virtanen M, Heinonen OP (1991) Low-level air pollution and upper respiratory infections in children. Am J Public Health 81:1060–1063
doi: 10.2105/AJPH.81.8.1060
Jaakkola JJ, Partti-Pellinen K, Marttila O, Miettinen P, Vilkka V, Haahtela T (1999) The South Karelia Air Pollution Study: changes in respiratory health in relation to emission reduction of malodorous sulfur compounds from pulp mills. Arch Environ Health 54:254–263. https://doi.org/10.1080/00039899909602483
doi: 10.1080/00039899909602483
Janes H, Sheppard L, Lumley T (2005) Overlap bias in the case-crossover design, with application to air pollution exposures. Stat Med 24(2):285–300
doi: 10.1002/sim.1889
Katsouyanni K, Touloumi G, Samoli E, Gryparis A, Le Tertre A et al (2001) Confounding effect modification in the short-term effects of ambient particles on total mortality: results from 29 European cities within the APHEA 2 project. Epidemiology 12:521–531
doi: 10.1097/00001648-200109000-00011
Legator MS, Singleton CR, Morris DL, Philips DL (2001) Health effects from chronic low-level exposure to hydrogen sulfide. Arch Environ Health 56:123–131. https://doi.org/10.1080/00039890109604063
doi: 10.1080/00039890109604063
Lewis RJ, Copley GB (2015) Chronic low-level hydrogen sulfide exposure and potential effects on human health: a review of the epidemiological evidence. Crit Rev Toxicol 45:93–123. https://doi.org/10.3109/10408444.2014.971943
doi: 10.3109/10408444.2014.971943
Lim E, Mbowe O, Lee AS, Davis J (2016) Effect of environmental exposure to hydrogen sulfide on central nervous system and respiratory function: a systematic review of human studies. Int J Occup Environ Health 22:80–90. https://doi.org/10.1080/10773525.2016.1145881
doi: 10.1080/10773525.2016.1145881
Lin LI (1989) A concordance correlation coefficient to evaluate reproducibility. Biometrics 45(1):255–268
doi: 10.2307/2532051
Lu Y, Zeger SL (2007) On the equivalence of case-crossover and time series methods in environmental epidemiology. Biostatistics 8(2):337–344
doi: 10.1093/biostatistics/kxl013
Lumley T, Levy D (2000) Bias in the case-crossover design: implications for studies of air pollution. Environmetrics 11:689–704
doi: 10.1002/1099-095X(200011/12)11:6<689::AID-ENV439>3.0.CO;2-N
Lund JW, Boyd TL (2016) Direct utilization of geothermal energy 2015 worldwide review. Geothermics 60:66–93
doi: 10.1016/j.geothermics.2015.11.004
Maclure M (1991) The case-crossover design: a method for studying transient effects on the risk of acute events. Am J Epidemiol 133:144–153
doi: 10.1093/oxfordjournals.aje.a115853
Marttila O, Jaakkola JJ, Vilkka V, Jäppinen P, Haahtela T (1994) The South Karelia Air Pollution Study: the effects of malodorous sulfur compounds from pulp mills on respiratory and other symptoms in children. Environ Res 66:152–159. https://doi.org/10.1006/enrs.1994.1051
doi: 10.1006/enrs.1994.1051
Minichilli F, Nuvolone D, Bustaffa E, Cipriani F, Vigotti MA, Bianchi F (2012) State of health of populations residing in geothermal areas of Tuscany. Epidemiol Prev 36(5 Suppl. 1):1–104
Moore PK, Whiteman M (eds) (2015) Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide. Springer, London
Navidi W (1998) Bidirectional case-crossover designs for exposures with time trends. Biometrics 54(2):596–605
doi: 10.2307/3109766
Nuvolone D, Santini M, Pepe P, Cipriani F (2016) Impacts of geocoding quality in environmental epidemiology studies: two case-studies in Tuscany Region (Central Italy). Epidemiol Prev 40:44–50
Nuvolone D, Petri D, Pepe P, Voller F (2019) Health effects associated with chronic exposure to low-level hydrogen sulfide from geothermoelectric power plants. A residential cohort study in the geothermal area of Mt. Amiata in Tuscany. Publication in progress https://www.sciencedirect.com/science/article/pii/S0048969718352562?via%3Dihub
Partti-Pellinen K, Marttila O, Vilkka V, Jaakkola JJ, Jäppinen P, Haahtela T (1996) The South Karelia Air Pollution Study: effects of low-level exposure to malodorous sulfur compounds on symptoms. Arch Environ Health 51:315–320. https://doi.org/10.1080/00039896.1996.9936031
doi: 10.1080/00039896.1996.9936031
Polhemus DJ, Calvert JW, Butler J, Lefer DJ (2014) The cardioprotective actions of hydrogen sulfide in acute myocardial infarction and heart failure. Scientifica. https://doi.org/10.1155/2014/768607
doi: 10.1155/2014/768607
Razzano F, Cei M (2015) Geothermal power generation in Italy 2010–2014 update report. In: Proceedings world geothermal congress 2015 Melbourne, Australia, 19–25 April 2015
Reed BR, Crane J, Garrett N, Woods DL, Bates MN (2014) Chronic ambient hydrogen sulfide exposure and cognitive function. Neurotoxicol Teratol 42:68–76
doi: 10.1016/j.ntt.2014.02.002
Regional Agency for the Environmental Protection of Tuscany (ARPAT) (2002) Monitoraggio aree geotermiche. ARPAT, Firenze
Regional Agency for the Environmental Protection of Tuscany (ARPAT) (2009) Monitoraggio delle aree geotermiche: Rapporto finale biennio 2007–2008. ARPAT, Firenze
Regional Agency for the Environmental Protection of Tuscany (ARPAT) (2014) Monitoraggio delle aree geotermiche toscane: Concentrazioni di idrogeno solforato nelle aree geotermiche toscane. Validazione dati ENEL e monitoraggi, ARPAT, Firenze
Regional Agency for the Environmental Protection of Tuscany (ARPAT) (2015) Monitoraggio aree geotermiche. ARPAT, Firenze
Rossi OV, Kinnula VL, Tienari J, Huhti E (1993) Association of severe asthma attacks with weather, pollen, and air pollutants. Thorax 48(3):244–248
doi: 10.1136/thx.48.3.244
Samet JM, Zeger SL, Dominici F, Curriero F, Coursac I et al (2000) The national morbidity, mortality, and air pollution study. Part II: morbidity and mortality from air pollution in the United States (with discussion). Res Rep Health Effects Inst 94:5–79
Schwartz J (2004) The effects of particulate air pollution on daily deaths: a multi-city case crossover analysis. Occup Environ Med 61(12):956–961
doi: 10.1136/oem.2003.008250
Shortall R, Davidsdottir B, Axelssonc G (2015) Geothermal energy for sustainable development: a review of sustainability impacts and assessment frameworks. Renew Sustain Energy Rev 44:391–406
doi: 10.1016/j.rser.2014.12.020
Somma R, Granieri D, Troise C, Terranova C, De Natale G, Pedone M (2017) Modelling of hydrogen sulfide dispersion from the geothermal power plants of Tuscany (Italy). Sci Total Environ 583:408–420. https://doi.org/10.1016/j.scitotenv.2017.01.084
doi: 10.1016/j.scitotenv.2017.01.084
Stafoggia M, Forastiere F, Faustini A, Biggeri A, Bisanti L, Cadum E, Cernigliaro A, Mallone S, Pandolfi P, Serinelli M, Tessari R, Vigotti MA, Perucci CA (2010) Susceptibility factors to ozone-related mortality: a population-based case-crossover analysis. Am J Respir Crit Care Med 182(3):376–384
doi: 10.1164/rccm.200908-1269OC
Sterne JA, Davey Smith G (2001) Sifting the evidence-what's wrong with significance tests? BMJ 322(7280):226–231
doi: 10.1136/bmj.322.7280.226
Testai L, Marino A, Piano I et al (2016) The novel H(2)S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia/reperfusion injury through activation of mitoK(ATP) channels and reduction of oxidative stress. Pharmacol Res 113:290–299. https://doi.org/10.1016/j.phrs.2016.09.006
doi: 10.1016/j.phrs.2016.09.006
World Health Organization (2000) Air quality guidelines for Europe; 2 ed. WHO regional publications 91:146–8
World Health Organization (2003) Concise international chemical assessment document 53 hydrogen sulfide: human health aspects. WHO, Geneva
Zanobetti A, Schwartz J (2005) The effect of particulate air pollution on emergency admissions for myocardial infarction: a multicity case-crossover analysis. Environ Health Perspect 113(8):978–982. https://doi.org/10.1289/ehp.7550
doi: 10.1289/ehp.7550
Zeger SL, Thomas D, Dominici F, Samet JM, Schwartz J, Dockery D, Cohen A (2000) Exposure measurement error in time-series studies of air pollution: concepts and consequences. Environ Health Perspect 108(5):419–426
doi: 10.1289/ehp.00108419

Auteurs

Daniela Nuvolone (D)

Epidemiology Unit, Regional Health Agency of Tuscany, Via Pietro Dazzi 1, 50124, Florence, Italy. daniela.nuvolone@ars.toscana.it.

Davide Petri (D)

Epidemiology Unit, Regional Health Agency of Tuscany, Via Pietro Dazzi 1, 50124, Florence, Italy.

Annibale Biggeri (A)

Department of Statistics, Computer Science, Applications "G. Parenti", University of Florence, Viale Morgagni 59, 50134, Florence, Italy.

Fabio Barbone (F)

Institute for Maternal and Child Health, IRCCS Burlo Garofolo, via dell'Istria 65/1, 34137, Trieste, Italy.

Fabio Voller (F)

Epidemiology Unit, Regional Health Agency of Tuscany, Via Pietro Dazzi 1, 50124, Florence, Italy.

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