High strength brushite bioceramics obtained by selective regulation of crystal growth with chiral biomolecules.

Calcium Phosphates / chemical synthesis Ceramics / chemical synthesis Compressive Strength Crystallization Materials Testing Molecular Dynamics Simulation Stereoisomerism Tartrates / chemistry
Brushite ceramic Chirality Crystal growth Mechanical properties Tartaric acid

Journal

Acta biomaterialia
ISSN: 1878-7568
Titre abrégé: Acta Biomater
Pays: England
ID NLM: 101233144

Informations de publication

Date de publication:
01 04 2020
Historique:
received: 13 09 2019
revised: 27 01 2020
accepted: 30 01 2020
pubmed: 9 2 2020
medline: 31 3 2021
entrez: 9 2 2020
Statut: ppublish

Résumé

Chirality seems to play a key role in mineralization. Indeed, in biominerals, the biomolecules that guide the formation and organization of inorganic crystals and help construct materials with exceptional mechanical properties, are homochiral. Here, we show that addition of homochiral l-(+)-tartaric acid improved the mechanical properties of brushite bioceramics by decreasing their crystal size, following the classic Hall-Petch strengthening effect; d-(-)-tartaric acid had the opposite effect. Adding l-(+)-Tar increased both the compressive strength (26 MPa) and the fracture toughness (0.3 MPa m

Identifiants

DOI: 10.1016/j.actbio.2020.01.047 PMID: 32035283
pubmed: 32035283
pii: S1742-7061(20)30065-9
doi: 10.1016/j.actbio.2020.01.047
pii:
doi:

Substances chimiques

Calcium Phosphates 0
Tartrates 0
calcium phosphate, dibasic, dihydrate O7TSZ97GEP
tartaric acid W4888I119H

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

351-359

Informations de copyright

Copyright © 2020. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no competing interests.

Auteurs

Hanan Moussa (H)

Faculty of Dentistry, McGill University, Montreal, QC, H3A 0C7, Canada; Faculty of Dentistry, Benghazi University, Benghazi, 9504, Libya.

Wenge Jiang (W)

Faculty of Dentistry, McGill University, Montreal, QC, H3A 0C7, Canada; Department of Chemistry, Tianjin Key Laboratory of Molecular Optoelectronic Sciences, and Tianjin Collaborative Innovation Center of Chemical Science & Engineering, Tianjin University, Tianjin, 300072, PR China.

Ammar Alsheghri (A)

Department of Mining and Materials Engineering, McGill University, Montreal, QC, H3A 0C5, Canada.

Alaa Mansour (A)

Faculty of Dentistry, McGill University, Montreal, QC, H3A 0C7, Canada.

Amir El Hadad (AE)

Faculty of Dentistry, McGill University, Montreal, QC, H3A 0C7, Canada; Physics Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, 11884, Egypt.

Haihua Pan (H)

Qiushi Academy for Advanced Studies, Zhejiang University, Hangzhou, Zhejiang, 310027, PR China.

Ruikang Tang (R)

Qiushi Academy for Advanced Studies, Zhejiang University, Hangzhou, Zhejiang, 310027, PR China; Center for Biomaterials and Biopathways, Zhejiang University, Hangzhou, Zhejiang, 310027, PR China.

Jun Song (J)

Department of Mining and Materials Engineering, McGill University, Montreal, QC, H3A 0C5, Canada.

Javier Vargas (J)

Department of Anatomy and Cell Biology, Faculty of Medicine, McGill University, Montreal, QC, H3A 0C7, Canada.

Marc D McKee (MD)

Faculty of Dentistry, McGill University, Montreal, QC, H3A 0C7, Canada; Department of Anatomy and Cell Biology, Faculty of Medicine, McGill University, Montreal, QC, H3A 0C7, Canada.

Faleh Tamimi (F)

Faculty of Dentistry, McGill University, Montreal, QC, H3A 0C7, Canada. Electronic address: faleh.tamimimarino@mcgill.ca.

Articles similaires

Atomic view of photosynthetic metabolite permeability pathways and confinement in synthetic carboxysome shells.

Daipayan Sarkar, Christopher Maffeo, Markus Sutter et al.
1.00
Photosynthesis Ribulose-Bisphosphate Carboxylase Carbon Dioxide Molecular Dynamics Simulation Cyanobacteria

Hemiarthroplasty in young patients.

Hazimah Mahmud, Dong Wang, Andra Topan-Rat et al.
1.00
Humans Male Hemiarthroplasty Middle Aged Aged

Study on the mechanical properties of granite responses of cyclic heating and water cooling considering microcosmic and energy.

Xiaokang Liang, Hanxiang Liu, Yong Yuan et al.
1.00
Silicon Dioxide Water Hot Temperature Compressive Strength X-Ray Diffraction

Drug repurposing against fucosyltransferase-2 via docking, STD-NMR, and molecular dynamic simulation studies.

Muhammad Atif, Humaira Zafar, Atia-Tul- Wahab et al.
1.00
Fucosyltransferases Drug Repositioning Molecular Docking Simulation Molecular Dynamics Simulation Humans

Classifications MeSH

questionsmedicales.fr › Produits chimiques inorganiques › Composés du phosphore › Acides du phosphore › Acides phosphoriques › Phosphates › Phosphates de calcium › High strength brushite bioceramics obtained by...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Céramiques › High strength brushite bioceramics obtained by...
questionsmedicales.fr › Phénomènes physiques › Phénomènes mécaniques › Résistance à la compression › High strength brushite bioceramics obtained by...
questionsmedicales.fr › Phénomènes chimiques › Cristallisation › High strength brushite bioceramics obtained by...
questionsmedicales.fr › Techniques d'investigation › Test de matériaux › High strength brushite bioceramics obtained by...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire › High strength brushite bioceramics obtained by...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes de chimie organique › Isomérie › Stéréoisomérie › High strength brushite bioceramics obtained by...
questionsmedicales.fr › Glucides › Oses acides › Tartrates › High strength brushite bioceramics obtained by...