Immunotherapy of lymphomas.
Journal
The Journal of clinical investigation
ISSN: 1558-8238
Titre abrégé: J Clin Invest
Pays: United States
ID NLM: 7802877
Informations de publication
Date de publication:
01 04 2020
01 04 2020
Historique:
pubmed:
11
2
2020
medline:
31
12
2020
entrez:
11
2
2020
Statut:
ppublish
Résumé
Lymphoid malignancies typically promote an infiltrate of immune cells at sites involved by the disease. While some of the immune cells present in lymphoma have effector function, the immune system is unable to eradicate the malignant clone. Therapies that optimize immune function therefore have the potential to improve the outcome of lymphoma patients. In this Review, we discuss immunologic approaches that directly target the malignant cell as well as approaches to optimize both the innate and adaptive immune response to the tumor. While many of these therapies have shown single-agent activity, the future will clearly require thoughtful combinations of these approaches.
Identifiants
pubmed: 32039913
pii: 129206
doi: 10.1172/JCI129206
pmc: PMC7108914
doi:
pii:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1576-1585Références
N Engl J Med. 2018 Sep 6;379(10):934-947
pubmed: 30184451
Br J Haematol. 2016 Jun;173(5):722-30
pubmed: 27010483
Lancet. 2017 Aug 5;390(10094):555-566
pubmed: 28600132
Blood. 2001 Jan 1;97(1):101-6
pubmed: 11133748
Clin Cancer Res. 2012 Mar 15;18(6):1611-8
pubmed: 22271878
Lancet Oncol. 2018 Sep;19(9):1192-1204
pubmed: 30100375
Blood. 2005 Dec 1;106(12):3725-32
pubmed: 16123223
Blood. 2017 Jun 29;129(26):3419-3427
pubmed: 28424162
Clin Cancer Res. 2019 Dec 15;25(24):7363-7369
pubmed: 31420358
Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):E966-72
pubmed: 25730880
J Clin Oncol. 2018 May 10;36(14):1428-1439
pubmed: 29584546
Blood. 2010 Feb 4;115(5):925-35
pubmed: 19880495
Nat Med. 2019 May;25(5):814-824
pubmed: 30962585
Blood. 2014 Jul 10;124(2):188-95
pubmed: 24876563
J Clin Oncol. 2011 Jul 10;29(20):2787-94
pubmed: 21632504
Nat Med. 2017 Dec;23(12):1416-1423
pubmed: 29131157
J Clin Oncol. 2014 Jun 10;32(17):1797-803
pubmed: 24799467
Blood. 2002 Mar 1;99(5):1517-26
pubmed: 11861263
Lancet Oncol. 2016 Sep;17(9):1283-94
pubmed: 27451390
Blood. 1998 Sep 1;92(5):1549-55
pubmed: 9716582
Oncotarget. 2017 Jul 12;8(51):89256-89268
pubmed: 29179517
N Engl J Med. 2018 Nov 01;379(18):1711-1721
pubmed: 30380386
N Engl J Med. 2017 Jul 6;377(1):89-91
pubmed: 28679093
J Clin Oncol. 2014 Apr 10;32(11):1157-63
pubmed: 24616310
Ann Oncol. 2017 Nov 1;28(11):2806-2812
pubmed: 28945884
J Clin Oncol. 2012 Mar 10;30(8):837-42
pubmed: 22312108
Mol Ther. 2017 Jan 4;25(1):285-295
pubmed: 28129122
J Clin Oncol. 2016 Aug 10;34(23):2698-704
pubmed: 27269947
Cancer Immunol Immunother. 2018 Mar;67(3):483-494
pubmed: 29218366
Haematologica. 2018 Aug;103(8):1351-1358
pubmed: 29748443
J Clin Oncol. 2015 Nov 1;33(31):3635-40
pubmed: 26304886
BMC Cancer. 2018 Sep 26;18(1):929
pubmed: 30257649
J Clin Invest. 2017 Sep 1;127(9):3462-3471
pubmed: 28805662
Leuk Lymphoma. 2015;56(10):2863-9
pubmed: 25707288
Cancer Sci. 2012 May;103(5):933-8
pubmed: 22335424
Clin Cancer Res. 2019 Dec 1;25(23):6986-6994
pubmed: 31685491
Clin Cancer Res. 2017 Mar 1;23(5):1156-1166
pubmed: 27582488
Int J Hematol. 2020 Mar;111(3):409-416
pubmed: 31858429
N Engl J Med. 2018 Jan 25;378(4):331-344
pubmed: 29224502
Nat Biotechnol. 2018 Oct;36(9):847-856
pubmed: 30102295
N Engl J Med. 2010 Nov 4;363(19):1812-21
pubmed: 21047225
Clin Immunol. 2014 Dec;155(2):160-75
pubmed: 25444722
Blood Adv. 2019 Apr 9;3(7):1145-1153
pubmed: 30962222
Lancet Oncol. 2019 Jan;20(1):31-42
pubmed: 30518502
Clin Adv Hematol Oncol. 2014 Aug;12(8 Suppl 16):15-8
pubmed: 25768997
Blood. 2010 Oct 28;116(17):3268-77
pubmed: 20628145
Blood. 2017 Jul 20;130(3):285-296
pubmed: 28539325
Haematologica. 2020 Apr;105(4):e190-e193
pubmed: 31399525
Nature. 2017 Mar 2;543(7643):113-117
pubmed: 28225754
Blood. 2012 Jan 12;119(2):355-63
pubmed: 22045986
J Clin Oncol. 2013 Feb 10;31(5):573-83
pubmed: 23295790
J Clin Invest. 2016 Jun 1;126(6):2123-38
pubmed: 27111235
Leuk Lymphoma. 2012 Apr;53(4):575-80
pubmed: 22098403
J Invest Dermatol. 2008 Nov;128(11):2631-9
pubmed: 18480841
Blood. 2017 Jun 8;129(23):3071-3073
pubmed: 28356247
Blood. 2017 Apr 27;129(17):2437-2442
pubmed: 28188133
Ann Oncol. 2012 Sep;23(9):2356-62
pubmed: 22357442
Blood. 2015 Jan 1;125(1):82-9
pubmed: 25293773
Blood. 2012 Apr 26;119(17):3940-50
pubmed: 22308288
Blood. 2016 Mar 17;127(11):1410-6
pubmed: 26755709
J Clin Oncol. 2012 Jun 20;30(18):2190-6
pubmed: 22614995
Sci Transl Med. 2016 Sep 7;8(355):355ra116
pubmed: 27605551
N Engl J Med. 2002 Jan 24;346(4):235-42
pubmed: 11807147
J Vis Exp. 2019 Jul 22;(149):
pubmed: 31380838
J Clin Oncol. 2020 Jan 1;38(1):20-28
pubmed: 31532724
J Clin Oncol. 2017 Jul 1;35(19):2125-2132
pubmed: 28441111
Blood. 2009 Jan 1;113(1):18-27
pubmed: 18809757
Mayo Clin Proc. 2015 Aug;90(8):1152-63
pubmed: 26250731
J Clin Oncol. 2014 Mar 10;32(8):798-808
pubmed: 24344220
J Clin Oncol. 2019 Feb 20;37(6):481-489
pubmed: 30620669
J Hematol Oncol. 2018 Jan 31;11(1):15
pubmed: 29386072
N Engl J Med. 2017 Oct 5;377(14):1331-1344
pubmed: 28976863
Blood. 2015 Aug 20;126(8):983-92
pubmed: 26056165
N Engl J Med. 2017 Dec 28;377(26):2545-2554
pubmed: 29226764
Blood. 2007 Oct 15;110(8):2838-45
pubmed: 17609424
N Engl J Med. 2019 Jan 3;380(1):45-56
pubmed: 30501490
Pediatr Transplant. 2018 Mar;22(2):
pubmed: 29388302
Haematologica. 2018 May;103(5):e215-e218
pubmed: 29419431
Nat Med. 2018 May;24(5):563-571
pubmed: 29713085
Lancet. 2019 Jan 19;393(10168):229-240
pubmed: 30522922
Eur J Immunol. 2006 Jun;36(6):1598-607
pubmed: 16708399
Blood. 2019 Feb 14;133(7):697-709
pubmed: 30463995
J Immunother. 2014 Apr;37(3):170-9
pubmed: 24598452
Clin Cancer Res. 2015 Aug 1;21(15):3428-35
pubmed: 25869385
Sci Rep. 2017 Sep 5;7(1):10541
pubmed: 28874817
Oncoimmunology. 2015 Nov 11;5(4):e1115178
pubmed: 27141397
J Clin Oncol. 2018 Aug 1;36(22):2259-2266
pubmed: 29584548
N Engl J Med. 2014 Mar 20;370(12):1101-10
pubmed: 24401022
BMC Cancer. 2018 Feb 13;18(1):187
pubmed: 29439670
Cell Rep. 2018 May 15;23(7):2130-2141
pubmed: 29768210
Nat Rev Clin Oncol. 2018 Jan;15(1):47-62
pubmed: 28925994
Nat Rev Cancer. 2012 Mar 22;12(4):252-64
pubmed: 22437870
J Clin Oncol. 2012 Jun 20;30(18):2183-9
pubmed: 22454421
Leuk Lymphoma. 2015;56(9):2498-504
pubmed: 25651421
Hum Vaccin Immunother. 2017 Jun 3;13(6):1-6
pubmed: 28272989
J Clin Oncol. 1998 Aug;16(8):2825-33
pubmed: 9704735
Blood. 2009 Jun 18;113(25):6392-402
pubmed: 19377047
J Clin Oncol. 2018 Apr 1;36(10):942-950
pubmed: 29394125
Nat Rev Cancer. 2014 Aug;14(8):517-34
pubmed: 25008267
Mol Ther. 2015 Aug;23(8):1401-1409
pubmed: 26017177
J Clin Oncol. 2010 Oct 1;28(28):4324-32
pubmed: 20697067
Clin Cancer Res. 2014 Jan 1;20(1):213-20
pubmed: 24132920
Am J Hematol. 2019 Oct;94(10):E273-E275
pubmed: 31342556
Blood. 2017 Jul 20;130(3):267-270
pubmed: 28490569
N Engl J Med. 2017 Dec 28;377(26):2531-2544
pubmed: 29226797
J Immunother. 2009 Jul-Aug;32(6):622-31
pubmed: 19483647
Lancet Haematol. 2019 Jan;6(1):e12-e19
pubmed: 30612710
J Clin Oncol. 2017 Nov 1;35(31):3529-3537
pubmed: 28796588
J Clin Oncol. 2016 Nov 1;34(31):3733-3739
pubmed: 27354476
Blood. 2013 Oct 10;122(15):2539-49
pubmed: 23886836
Br J Haematol. 2018 Aug;182(4):583-586
pubmed: 28677896
J Clin Oncol. 2009 Jun 20;27(18):3036-43
pubmed: 19414675
N Engl J Med. 2015 Jan 22;372(4):311-9
pubmed: 25482239
Nat Med. 1996 Jan;2(1):52-8
pubmed: 8564842
Blood Rev. 2019 Mar;34:45-55
pubmed: 30528964
Int J Radiat Oncol Biol Phys. 2019 Dec 1;105(5):1012-1021
pubmed: 31175906
Cancer. 2013 Nov 1;119(21):3797-804
pubmed: 23922187