Clinical Relevance of Immune Checkpoints on Circulating Tumor Cells in Breast Cancer.
CD47
CTCs
PBMCs
PD-L1
TILs
breast cancer
immune checkpoints
immune escape
immune response
liquid biopsy
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
06 Feb 2020
06 Feb 2020
Historique:
received:
24
12
2019
revised:
04
02
2020
accepted:
05
02
2020
entrez:
12
2
2020
pubmed:
12
2
2020
medline:
12
2
2020
Statut:
epublish
Résumé
The role of CD47 and PD-L1 expression on circulating tumor cells (CTCs) remains unclear, and it is currently unknown whether their distribution varies between the blood and tumor tissue in breast cancer (BC). In this study, CD47 and PD-L1 expression was investigated a) on peripheral blood mononuclear cell (PBMC) cytospins from early (
Identifiants
pubmed: 32041353
pii: cancers12020376
doi: 10.3390/cancers12020376
pmc: PMC7072621
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Hellenic Society of Medical Oncology
ID : Research_funding_2017
Organisme : Anticancer Research Support Association (ARSA), Heraklion, Greece
ID : N.3846/2010
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.
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