Gold nanoclusters elicit homeostatic perturbations in glioblastoma cells and adaptive changes of lysosomes.
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
/ drug effects
Cell Survival
/ drug effects
Glioblastoma
/ pathology
Gold
/ adverse effects
Homeostasis
/ drug effects
Humans
Lysosomes
/ drug effects
Metal Nanoparticles
/ administration & dosage
NF-E2-Related Factor 2
/ drug effects
Particle Size
Proteostasis
/ drug effects
Transcription Factors
/ drug effects
cell organelle
cellular stress response
lysosome positioning
nanomaterials
organellar pH
proteostasis
Journal
Theranostics
ISSN: 1838-7640
Titre abrégé: Theranostics
Pays: Australia
ID NLM: 101552395
Informations de publication
Date de publication:
2020
2020
Historique:
received:
17
06
2019
accepted:
03
10
2019
entrez:
12
2
2020
pubmed:
12
2
2020
medline:
14
4
2021
Statut:
epublish
Résumé
Unique physicochemical features place gold nanoclusters at the forefront of nanotechnology for biological and biomedical applications. To date, information on the interactions of gold nanoclusters with biological macromolecules is limited and restricts their use in living cells.
Identifiants
pubmed: 32042327
doi: 10.7150/thno.37674
pii: thnov10p1633
pmc: PMC6993243
doi:
Substances chimiques
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
0
NF-E2-Related Factor 2
0
NFE2L2 protein, human
0
TFEB protein, human
0
Transcription Factors
0
Gold
7440-57-5
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1633-1648Informations de copyright
© The author(s).
Déclaration de conflit d'intérêts
Competing Interests: The authors have declared that no competing interest exists.
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