Management of Takotsubo Syndrome: A Comprehensive Review.
acute coronary syndrome
cardiomyopathy
left ventricular outflow tract obstruction
takotsubo cardiomyopathy
takotsubo syndrome
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
03 Jan 2020
03 Jan 2020
Historique:
entrez:
12
2
2020
pubmed:
12
2
2020
medline:
12
2
2020
Statut:
epublish
Résumé
Takotsubo syndrome (TTS), also known as Takotsubo cardiomyopathy, is a transient left ventricular wall dysfunction that is often triggered by physical or emotional stressors. Although TTS is a rare disease with a prevalence of only 0.5% to 0.9% in the general population, it is often misdiagnosed as acute coronary syndrome. A diagnosis of TTS can be made using Mayo diagnostic criteria. The initial management of TTS includes dual antiplatelet therapy, anticoagulants, beta-blockers, angiotensin-converting enzyme inhibitors or aldosterone receptor blockers, and statins. Treatment is usually provided for up to three months and has a good safety profile. For TTS with complications such as cardiogenic shock, management depends on left ventricular outflow tract obstruction (LVOTO). In patients without LVOTO, inotropic agents can be used to maintain pressure, while inotropic agents are contraindicated in patients with LVOTO. In TTS with thromboembolism, heparin should be started, and patients should be bridged to warfarin for up to three months to prevent systemic emboli. Our comprehensive review discussed the management in detail, derived from the most recent literature from observational studies, systematic review, and meta-analyses.
Identifiants
pubmed: 32042529
doi: 10.7759/cureus.6556
pmc: PMC6996473
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e6556Informations de copyright
Copyright © 2020, Sattar et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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