Sensorimotor Induction of Auditory Misattribution in Early Psychosis.
Adult
Conflict, Psychological
Discrimination, Psychological
/ physiology
Feedback, Sensory
/ physiology
Female
Hallucinations
/ etiology
Humans
Male
Psychomotor Performance
/ physiology
Psychotic Disorders
/ complications
Robotics
Speech Perception
/ physiology
Touch Perception
/ physiology
Young Adult
early psychosis
predictive processing
sense of agency
sensorimotor conflict
source monitoring
Journal
Schizophrenia bulletin
ISSN: 1745-1701
Titre abrégé: Schizophr Bull
Pays: United States
ID NLM: 0236760
Informations de publication
Date de publication:
08 07 2020
08 07 2020
Historique:
pubmed:
12
2
2020
medline:
18
5
2021
entrez:
12
2
2020
Statut:
ppublish
Résumé
Dysfunction of sensorimotor predictive processing is thought to underlie abnormalities in self-monitoring producing passivity symptoms in psychosis. Experimentally induced sensorimotor conflict can produce a failure in bodily self-monitoring (presence hallucination [PH]), yet it is unclear how this is related to auditory self-monitoring and psychosis symptoms. Here we show that the induction of sensorimotor conflict in early psychosis patients induces PH and impacts auditory-verbal self-monitoring. Participants manipulated a haptic robotic system inducing a bodily sensorimotor conflict. In experiment 1, the PH was measured. In experiment 2, an auditory-verbal self-monitoring task was performed during the conflict. Fifty-one participants (31 early psychosis patients, 20 matched controls) participated in the experiments. The PH was present in all participants. Psychosis patients with passivity experiences (PE+) had reduced accuracy in auditory-verbal self-other discrimination during sensorimotor stimulation, but only when sensorimotor stimulation involved a spatiotemporal conflict (F(2, 44) = 6.68, P = .002). These results show a strong link between robotically controlled alterations in sensorimotor processing and auditory misattribution in psychosis and provide evidence for the role of sensorimotor processes in altered self-monitoring in psychosis.
Identifiants
pubmed: 32043142
pii: 5733158
doi: 10.1093/schbul/sbz136
pmc: PMC7345777
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
947-954Informations de copyright
© The Author(s) 2020. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com.
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