Changes of various insecticides during in vitro human digestion.
Digestive enzyme
Enteric bacteria
In vitro human digestion
Insecticide
Journal
Environmental science and pollution research international
ISSN: 1614-7499
Titre abrégé: Environ Sci Pollut Res Int
Pays: Germany
ID NLM: 9441769
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
15
08
2019
accepted:
04
02
2020
pubmed:
12
2
2020
medline:
11
7
2020
entrez:
12
2
2020
Statut:
ppublish
Résumé
This study was performed to determine the effects of in vitro human digestion on the concentrations of five insecticides, namely 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT), 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane (DDD), 2,2-bis(p-chlorophenyl)-1,1-dichloroethylene (DDE), bifenthrin, and fipronil. In vitro models included all the steps of human digestion, i.e., passage through the mouth, stomach, small intestine, and large intestine (with enteric bacteria). The concentrations of DDT and fipronil did not change (P > 0.05) until small intestinal digestion, whereas those of DDD, DDE, and bifenthrin decreased (P < 0.05) at each digestion step. The concentrations of all the insecticides decreased (P < 0.05) during the large intestinal digestion step with enteric bacteria, Lactobacillus sakei and Escherichia coli. In conclusion, the concentrations of all the tested insecticides decreased during all the steps of in vitro human digestion and were especially reduced by enteric bacteria during the large intestinal digestion step.
Identifiants
pubmed: 32043247
doi: 10.1007/s11356-020-07994-z
pii: 10.1007/s11356-020-07994-z
doi:
Substances chimiques
Insecticides
0
Dichlorodiphenyl Dichloroethylene
4M7FS82U08
DDT
CIW5S16655
Dichlorodiphenyldichloroethane
V14159DF29
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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