'Hospice inpatient deep vein thrombosis detection (HIDDen) in advanced non-malignant diseases': a longitudinal pilot study.
DVT
hospices
non-malignant
palliative care
thromboprophylaxis
venous thromboembolism
Journal
BMJ supportive & palliative care
ISSN: 2045-4368
Titre abrégé: BMJ Support Palliat Care
Pays: England
ID NLM: 101565123
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
17
09
2019
revised:
10
01
2020
accepted:
20
01
2020
pubmed:
13
2
2020
medline:
30
11
2022
entrez:
13
2
2020
Statut:
ppublish
Résumé
To gain preliminary data regarding the prevalence of proximal deep vein thrombosis (DVT) in those with non-malignant conditions admitted to specialist palliative care units (SPCUs). Data were collected as part of a prospective longitudinal observational study in five SPCUs in England, Wales and Northern Ireland (Registration: ISRCTN97567719) to estimate the prevalence of proximal femoral vein DVT in people admitted to SPCUs. The primary outcome for this exploratory substudy was the prevalence of DVT in patients with non-malignant palliative conditions. Consecutive consenting adults underwent bilateral femoral vein ultrasonography within 48 hours of admission. Data were collected on symptoms associated with venous thromboembolism. Patients were ineligible if the estimated prognosis was <5 days. Cross-sectional descriptive analysis was conducted on baseline data and prevalence estimates presented with 95% CIs. 1390 patients were screened, 28 patients had non-malignant disease and all were recruited. The mean age 68·8 (SD 12·0), range 43-86 years; men 61%; survival mean 86 (SD 108.5) range 1-345 days. No patient had a history of venous thromboembolism. Four (14%) were receiving thromboprophylaxis. Of 22 evaluable scans, 8 (36%, 95% CI: 17% to 59%) showed femoral vein DVT. The level of reported relevant symptoms (leg oedema, leg pain, chest pain and breathlessness) was high irrespective of the presence of DVT. Our exploratory data indicate one in three people admitted to an SPCU with non-malignant disease had a femoral vein DVT. Although definitive conclusions cannot be drawn, these data justify a larger prospective survey.
Identifiants
pubmed: 32046963
pii: bmjspcare-2019-002039
doi: 10.1136/bmjspcare-2019-002039
doi:
Substances chimiques
Anticoagulants
0
Types de publication
Observational Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e767-e770Subventions
Organisme : Marie Curie
ID : MCCC-FCO-11-C
Pays : United Kingdom
Organisme : Department of Health
ID : PB-PG-0614-34007
Pays : United Kingdom
Informations de copyright
© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: MW designed and teaches the Focussed Abdominal Ultrasound in Palliative Care training programme, running since 2007, which trained the research nurses for this study. SN has received speakers bureau fees from Pfizer, Daiichi Sankyo, Bayer and Advisory Board fees from Daiichi Sankyo.