A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation.


Journal

Case reports in psychiatry
ISSN: 2090-682X
Titre abrégé: Case Rep Psychiatry
Pays: United States
ID NLM: 101583308

Informations de publication

Date de publication:
2020
Historique:
received: 06 09 2019
revised: 10 01 2020
accepted: 16 01 2020
entrez: 13 2 2020
pubmed: 13 2 2020
medline: 13 2 2020
Statut: epublish

Résumé

Several studies report on traumatic history in Obsessive Compulsive Disorder (OCD) and comorbidity between Posttraumatic Stress Disorder (PTSD) and OCD. First-line pharmacological treatments for both OCD and PTSD are primarily based on antidepressants, including Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin-Noradrenaline Reuptake Inhibitors (SNRI) such as Venlafaxine for PTSD. Second-Generation Antipsychotic (SGA) augmentation has shown good outcomes for nonresponsive OCD cases. However, evidence on the use of SGA in PTSD is more limited. In the present paper, we report on comorbid OCD-PTSD successfully treated with aripiprazole augmentation of sertraline. Shared psychopathological and pharmacological aspects of the disorders are discussed.

Identifiants

pubmed: 32047692
doi: 10.1155/2020/2616492
pmc: PMC7007739
doi:

Types de publication

Case Reports

Langues

eng

Pagination

2616492

Informations de copyright

Copyright © 2020 Rodolfo Rossi et al.

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest.

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Auteurs

Rodolfo Rossi (R)

Chair of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

Cinzia Niolu (C)

Chair of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Psychiatry and Clinical Psychology Unit, Fondazione Policlinico Tor Vergata, Rome, Italy.

Alberto Siracusano (A)

Chair of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Psychiatry and Clinical Psychology Unit, Fondazione Policlinico Tor Vergata, Rome, Italy.

Alessandro Rossi (A)

Department of Applied Clinical Sciences and Biotechnologies, University of L'Aquila, Via Vetoio, 67100 L'Aquila, Italy.

Giorgio Di Lorenzo (G)

Chair of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Psychiatry and Clinical Psychology Unit, Fondazione Policlinico Tor Vergata, Rome, Italy.

Classifications MeSH