MASS SPECTROMETRY ANALYSIS OF DRUGS OF ABUSE: CHALLENGES AND EMERGING STRATEGIES.
ambient ionization mass spectrometry
drugs of abuse
forensic
gas chromatography-mass spectrometry (GC-MS)
liquid chromatography-mass spectrometry (LC-MS)
toxicology
Journal
Mass spectrometry reviews
ISSN: 1098-2787
Titre abrégé: Mass Spectrom Rev
Pays: United States
ID NLM: 8219702
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
15
09
2019
accepted:
22
01
2020
pubmed:
13
2
2020
medline:
25
2
2023
entrez:
13
2
2020
Statut:
ppublish
Résumé
Mass spectrometry has been the "gold standard" for drugs of abuse (DoA) analysis for many decades because of the selectivity and sensitivity it affords. Recent progress in all aspects of mass spectrometry has seen significant developments in the field of DoA analysis. Mass spectrometry is particularly well suited to address the rapidly proliferating number of very high potency, novel psychoactive substances that are causing an alarming number of fatalities worldwide. This review surveys advancements in the areas of sample preparation, gas and liquid chromatography-mass spectrometry, as well as the rapidly emerging field of ambient ionization mass spectrometry. We have predominantly targeted literature progress over the past ten years and present our outlook for the future. © 2020 Periodicals, Inc. Mass Spec Rev.
Substances chimiques
Illicit Drugs
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
703-744Informations de copyright
© 2020 John Wiley & Sons Ltd.
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