Good Fences Make Good Neighbors: Crumbs Regulates Rho-Kinase Dynamics to Assemble a Tissue Boundary.

Actomyosin Drosophila Proteins Morphogenesis Myosins rho-Associated Kinases

Journal

Developmental cell
ISSN: 1878-1551
Titre abrégé: Dev Cell
Pays: United States
ID NLM: 101120028

Informations de publication

Date de publication:
10 02 2020
Historique:
entrez: 13 2 2020
pubmed: 13 2 2020
medline: 25 7 2020
Statut: ppublish

Résumé

Boundary formation between nascent tissues prevents cell mixing, powering morphogenesis. In this issue of Developmental Cell, Sidor et al. (2020) describe a novel mechanism whereby the homophilic adhesion protein Crumbs regulates planar-polarized assembly of actomyosin cables at tissue boundaries by affecting dynamics of membrane recruitment of the myosin regulator Rho-kinase.

Identifiants

DOI: 10.1016/j.devcel.2020.01.018 PMID: 32049035
pubmed: 32049035
pii: S1534-5807(20)30050-2
doi: 10.1016/j.devcel.2020.01.018
pii:
doi:

Substances chimiques

Drosophila Proteins 0
Actomyosin 9013-26-7
rho-Associated Kinases EC 2.7.11.1
Myosins EC 3.6.4.1

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

255-256

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Hui-Chia Yu-Kemp (HC)

Department of Biology and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Mark Peifer (M)

Department of Biology and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: peifer@unc.edu.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines contractiles › Protéines du muscle › Actomyosine › Good Fences Make Good Neighbors: Crumbs...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines d'arthropode › Protéines d'insecte › Protéines de Drosophila › Good Fences Make Good Neighbors: Crumbs...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Morphogenèse › Good Fences Make Good Neighbors: Crumbs...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du cytosquelette › Protéines des microfilaments › Myosines › Good Fences Make Good Neighbors: Crumbs...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-Serine-Threonine Kinases › rho-Associated Kinases › Good Fences Make Good Neighbors: Crumbs...