Combination of diabetes mellitus and lack of habitual physical activity is a risk factor for functional disability in Japanese.
body mass index
disability
physical activity
Journal
BMJ open diabetes research & care
ISSN: 2052-4897
Titre abrégé: BMJ Open Diabetes Res Care
Pays: England
ID NLM: 101641391
Informations de publication
Date de publication:
01 2020
01 2020
Historique:
received:
12
09
2019
revised:
02
11
2019
accepted:
11
11
2019
entrez:
13
2
2020
pubmed:
13
2
2020
medline:
22
6
2021
Statut:
ppublish
Résumé
Declining healthy life expectancy due to functional disability is relevant and urgent because of its association with decreased quality of life and also for its enormous socioeconomic impact. The aim of this study is to examine the impact of diabetes, hypertension, dyslipidemia and physical activity habits on functional disability among community-dwelling Japanese adults. This is a population-based retrospective cohort study including 9673 people aged 39-98 years in Japan (4420, men). Functional disability was defined as a condition meeting Japan's new long-term care insurance certification requirements for the need of assistance in the activities of daily living whether by caregivers or assistive devices. Cox proportional-hazards regression model identified variables related to functional disability. Median follow-up was 3.7 years. During the study period, 165 disabilities occurred in the overall study population. Multivariate analysis showed that diabetes (HR 1.74 (95% CI 1.12 to 2.68)) and no physical activity habit (HR 1.83 (1.27 to 2.65)) presented increased risks for disability. HR for disability increased with the number of risk factors (HR of individuals with four conditions, 3.96 (1.59 to 9.99) vs individuals with none of those conditions as a reference). HR for disability among patients with diabetes with and without a physical activity habit was 1.68 (0.70 to 4.04) and 3.19 (1.79 to 5.70), respectively, compared with individuals without diabetes with a physical activity habit. The combination of diabetes and lack of habitual physical activity is predictive of functional disability in Japanese. Habitual physical activity attenuates the risk of functional disability in patients with diabetes.
Identifiants
pubmed: 32049629
pii: 8/1/e000901
doi: 10.1136/bmjdrc-2019-000901
pmc: PMC7039616
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
J Am Med Dir Assoc. 2012 Jul;13(6):507-11
pubmed: 22572554
Nihon Koshu Eisei Zasshi. 2011 Jan;58(1):3-13
pubmed: 21409818
Lancet Diabetes Endocrinol. 2013 Oct;1(2):106-14
pubmed: 24622316
J Diabetes Complications. 2010 Sep-Oct;24(5):345-53
pubmed: 20656522
JAMA. 1996 May 22-29;275(20):1571-6
pubmed: 8622248
Atherosclerosis. 1996 Jul;124 Suppl:S1-9
pubmed: 8831910
J Am Geriatr Soc. 2007 Sep;55(9):1458-63
pubmed: 17767690
JAMA. 2004 Nov 24;292(20):2495-9
pubmed: 15562129
J Am Geriatr Soc. 2014 May;62(5):913-8
pubmed: 24779403
J Am Geriatr Soc. 2005 Mar;53(3):522-7
pubmed: 15743300
J Gerontol A Biol Sci Med Sci. 2014 Jul;69(7):843-51
pubmed: 24270063
BMJ. 2018 Sep 5;362:k3359
pubmed: 30185425
J Gerontol A Biol Sci Med Sci. 2009 Jan;64(1):61-8
pubmed: 19164276
Endocr Rev. 2015 Apr;36(2):194-213
pubmed: 25738213
Lancet. 1998 Dec 5;352(9143):1801-7
pubmed: 9851379
Ther Adv Neurol Disord. 2009 Jul;2(4):241-60
pubmed: 21179532
Cochrane Database Syst Rev. 2009 Jul 08;(3):CD002759
pubmed: 19588334
J Gerontol A Biol Sci Med Sci. 2018 Apr 17;73(5):622-629
pubmed: 29106478
Nutr Res. 2017 Jul;43:3-15
pubmed: 28739051
J Am Med Dir Assoc. 2015 Nov 1;16(11):1003.e7-11
pubmed: 26482055
Arch Intern Med. 2001 Jun 11;161(11):1413-9
pubmed: 11386890
Circulation. 2005 Nov 29;112(22):3384-90
pubmed: 16301345
Diabetes Care. 2019 Apr;42(4):507-513
pubmed: 30692240
Lancet Neurol. 2006 Jan;5(1):64-74
pubmed: 16361024
J Epidemiol. 2012;22(6):543-50
pubmed: 23117222
Circulation. 2010 Aug 17;122(7):743-52
pubmed: 20713909
Diabetes Care. 2016 Sep;39(9):1643-9
pubmed: 27555623
Lancet. 2015 Nov 28;386(10009):2145-91
pubmed: 26321261
Arch Gerontol Geriatr. 2013 Nov-Dec;57(3):328-32
pubmed: 23566448