EEG microstates associated with intra- and inter-subject alpha variability.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
12 02 2020
Historique:
received: 11 09 2018
accepted: 16 01 2020
entrez: 14 2 2020
pubmed: 14 2 2020
medline: 18 11 2020
Statut: epublish

Résumé

Variation of the magnitude of posterior alpha rhythm (8-12 Hz) has functional and behavioural effects in sensory processing and cognitive performances. Electrical brain activity, as revealed by electroencephalography (EEG), can be represented by a sequence of microstates of about 40-120 ms duration, in which distributed neural pools are synchronously active and generate stable spatial potential topographies on the scalp. Microstate dynamics may reflect transitions between global states characterized by selective inhibition of specific intra-cortical regions, mediated by alpha activity. We investigated the intra-subject and inter-subject relationship between microstate features and alpha band. High-density EEG signals were acquired in 29 healthy subjects during ten minutes of eyes closed rest. Individual EEG signal epochs were classified into four groups depending on the amount of occipital alpha power, and microstate metrics (duration, coverage and frequency of occurrence) were calculated and compared across groups. Correlations between alpha power and microstate metrics between individuals were also performed. To assess if microstate parameter variations are specific for the alpha band, the same analysis was also performed for theta and beta bands, as well as for global field power. We observed an increase in the metrics of microstate, previously associated to the visual system, with the level of intra-subject amplitude alpha oscillations, together with lower coverage of microstate associated with executive attention network and a higher frequency of microstate associated with task negative network. Other modulation effects of broad-band EEG power level on microstate metrics were observed. These effects are not specific for the alpha band, since they can equally be attributed to fluctuations in other frequency bands. We can interpret our results as a regulation mechanism mediated by posterior alpha level, dynamically interacting with other frequency bands, responsible for the switching between active areas.

Identifiants

pubmed: 32051420
doi: 10.1038/s41598-020-58787-w
pii: 10.1038/s41598-020-58787-w
pmc: PMC7015936
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2469

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Auteurs

Pierpaolo Croce (P)

Department of Neuroscience, Imaging and Clinical Sciences,"G. d'Annunzio" University of Chieti-Pescara, Chieti-Pescara, Italy.

Angelica Quercia (A)

Department of Neuroscience, Imaging and Clinical Sciences,"G. d'Annunzio" University of Chieti-Pescara, Chieti-Pescara, Italy.

Sergio Costa (S)

Department of Neuroscience, Imaging and Clinical Sciences,"G. d'Annunzio" University of Chieti-Pescara, Chieti-Pescara, Italy.

Filippo Zappasodi (F)

Department of Neuroscience, Imaging and Clinical Sciences,"G. d'Annunzio" University of Chieti-Pescara, Chieti-Pescara, Italy. f.zappasodi@unich.it.
Institute for Advanced Biomedical Technologies, "G. d'Annunzio" University of Chieti-Pescara, Chieti-Pescara, Italy. f.zappasodi@unich.it.

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