Does Reconstruction with Reimplantation of Sterilized Tumor Bone Provide Survival Benefit in Diaphyseal Osteosarcoma?


Journal

Sarcoma
ISSN: 1357-714X
Titre abrégé: Sarcoma
Pays: Egypt
ID NLM: 9709257

Informations de publication

Date de publication:
2020
Historique:
received: 06 10 2019
revised: 10 12 2019
accepted: 23 12 2019
entrez: 14 2 2020
pubmed: 14 2 2020
medline: 14 2 2020
Statut: epublish

Résumé

Does reimplantation of sterilized tumor bone for reconstruction provide outcome benefits in intercalary osteosarcoma based on the potential immunogenic effect of reimplanted sterilized tumor tissue? Of 720 cases of surgically treated high-grade osteosarcoma patients treated at our institute from 2006 to 2013, 61 had predominantly diaphyseal disease. All patients were nonmetastatic at presentation. Patient and tumor characteristics, treatment details, and local recurrence-free, metastasis-free, and overall survival were compared for 24 patients who had reconstruction with sterilized tumor bone reimplantation vs 37 who did not. Both the groups were well matched in terms of baseline characteristics. Means were compared with the

Identifiants

pubmed: 32051679
doi: 10.1155/2020/4092790
pmc: PMC6995309
doi:

Types de publication

Journal Article

Langues

eng

Pagination

4092790

Informations de copyright

Copyright © 2020 Prakash Nayak et al.

Déclaration de conflit d'intérêts

The authors declare there are no conflicts of interest regarding the publication of this paper.

Références

Cryobiology. 2003 Jun;46(3):238-45
pubmed: 12818213
Indian J Med Res. 2014 Apr;139(4):585-97
pubmed: 24927346
Cryobiology. 2001 Feb;42(1):49-58
pubmed: 11336489
Invest Urol. 1968 May;5(6):619-26
pubmed: 4988413
BMC Cancer. 2015 Apr 15;15:289
pubmed: 25884718
Ann Oncol. 2013 Oct;24(10):2676-80
pubmed: 23852310
J Surg Oncol. 2018 Feb;117(2):299-306
pubmed: 28833209
Gastroenterol Res Pract. 2016;2016:9251375
pubmed: 27051417
J Urol. 1972 Dec;108(6):933-5
pubmed: 5082750
Indian J Orthop. 2010 Oct;44(4):390-6
pubmed: 20924479
J Bone Joint Surg Br. 2008 Sep;90(9):1249-55
pubmed: 18757969
Sarcoma. 2017;2017:9710964
pubmed: 28659718
Int J Clin Oncol. 2011 Apr;16(2):109-17
pubmed: 21400111
Int J Radiat Oncol Biol Phys. 2004 Mar 1;58(3):862-70
pubmed: 14967443

Auteurs

Prakash Nayak (P)

Department of Surgical Oncology, Bone and Soft Tissue Disease Management Group, Tata Memorial Centre, Homi Bhabha National Institute, Parel, Mumbai 400012, India.

Ashish Gulia (A)

Department of Surgical Oncology, Bone and Soft Tissue Disease Management Group, Tata Memorial Centre, Homi Bhabha National Institute, Parel, Mumbai 400012, India.

Ajay Puri (A)

Department of Surgical Oncology, Bone and Soft Tissue Disease Management Group, Tata Memorial Centre, Homi Bhabha National Institute, Parel, Mumbai 400012, India.

Classifications MeSH