Moving proteins along in the cilium.

BBSome arl6 bos taurus cilia cryo-em human intraflagellar transport molecular biophysics structural biology

Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
13 02 2020
Historique:
received: 06 02 2020
accepted: 06 02 2020
entrez: 14 2 2020
pubmed: 14 2 2020
medline: 13 3 2021
Statut: epublish

Résumé

The structures of the bovine and human BBSome reveal that a conformational change is required to recruit the complex to the ciliary membrane.

Identifiants

pubmed: 32052743
doi: 10.7554/eLife.55254
pii: 55254
pmc: PMC7018505
doi:
pii:

Substances chimiques

Membrane Proteins 0

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Commentaires et corrections

Type : CommentOn
Type : CommentOn

Informations de copyright

© 2020, Petriman and Lorentzen.

Déclaration de conflit d'intérêts

NP, EL No competing interests declared

Références

Essays Biochem. 2018 Dec 7;62(6):753-763
pubmed: 30287585
Cell. 2010 Jun 25;141(7):1208-19
pubmed: 20603001
Bioscience. 2014 Dec 1;64(12):1126-1137
pubmed: 25960570
Trans Am Clin Climatol Assoc. 2010;121:172-81; discussion 181-2
pubmed: 20697559
Nat Struct Mol Biol. 2014 Dec;21(12):1035-41
pubmed: 25402481
Cell. 2007 Jun 15;129(6):1201-13
pubmed: 17574030
Elife. 2020 Jan 15;9:
pubmed: 31939736
Structure. 2019 Sep 3;27(9):1384-1394.e4
pubmed: 31303482
Elife. 2020 Jan 17;9:
pubmed: 31951201
J Cell Biol. 2009 Dec 28;187(7):1117-32
pubmed: 20038682

Auteurs

Narcis Adrian Petriman (NA)

Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.

Esben Lorentzen (E)

Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.

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Classifications MeSH