The CHORD protein CHP-1 regulates EGF receptor trafficking and signaling in
A431
C. elegans
CHORD
EGFR
HSP90
cell biology
chaperone
developmental biology
human
Journal
eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614
Informations de publication
Date de publication:
13 02 2020
13 02 2020
Historique:
received:
09
08
2019
accepted:
12
02
2020
pubmed:
14
2
2020
medline:
15
4
2021
entrez:
14
2
2020
Statut:
epublish
Résumé
The intracellular trafficking of growth factor receptors determines the activity of their downstream signaling pathways. Here, we show that the putative HSP-90 co-chaperone CHP-1 acts as a regulator of EGFR trafficking in
Identifiants
pubmed: 32053105
doi: 10.7554/eLife.50986
pii: 50986
pmc: PMC7062474
doi:
pii:
Substances chimiques
CHORDC1 protein, human
0
HSP90 Heat-Shock Proteins
0
Phosphate-Binding Proteins
0
EGFR protein, human
EC 2.7.10.1
ErbB Receptors
EC 2.7.10.1
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Swiss National Science Foundation
ID : 31003A-166580
Pays : Switzerland
Organisme : NIH HHS
ID : P40 OD010440
Pays : United States
Informations de copyright
© 2020, Haag et al.
Déclaration de conflit d'intérêts
AH, MW, AH, AH No competing interests declared
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