Eco-friendly synthesis of glutathione-capped CdTe/CdSe/ZnSe core/double shell quantum dots: their cytotoxicity and genotoxicity effects on Chinese hamster ovary cells.
Journal
Toxicology research
ISSN: 2045-452X
Titre abrégé: Toxicol Res (Camb)
Pays: England
ID NLM: 101587950
Informations de publication
Date de publication:
01 Nov 2019
01 Nov 2019
Historique:
received:
14
05
2019
accepted:
23
08
2019
entrez:
15
2
2020
pubmed:
15
2
2020
medline:
15
2
2020
Statut:
epublish
Résumé
In this work, we report green one-pot synthesis, cytotoxicity and genotoxicity of glutathione-capped CdTe/CdSe/ZnSe heterostructured quantum dots (QDs) using a label-free xCELLigence RTCA system as well as the Cytokinesis Blocked Micronucleus assay. The as-synthesised nanocrystals displayed good optical properties and were spherical in shape with an average particle diameter of 5.9 ± 1.13 nm. The intracellular uptake study showed that most of the as-synthesised glutathione stabilized QDs penetrated the cell membranes and were found randomly localized in the cytoplasm of Chinese Hamster Ovary (CHO) cells even at a lower concentration of 0.5 μg ml
Identifiants
pubmed: 32055393
doi: 10.1039/c9tx00113a
pii: c9tx00113a
pmc: PMC6991175
doi:
Types de publication
Journal Article
Langues
eng
Pagination
868-874Informations de copyright
This journal is © The Royal Society of Chemistry 2019.
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