Handheld volumetric manual compression-based quantitative microelastography.

freehand volumetric imaging handheld probe optical coherence elastography optical coherence tomography quantitative microelastography

Journal

Journal of biophotonics
ISSN: 1864-0648
Titre abrégé: J Biophotonics
Pays: Germany
ID NLM: 101318567

Informations de publication

Date de publication:
06 2020
Historique:
received: 26 11 2019
revised: 27 01 2020
accepted: 04 02 2020
pubmed: 15 2 2020
medline: 24 6 2021
entrez: 15 2 2020
Statut: ppublish

Résumé

Compression optical coherence elastography (OCE) typically requires a mechanical actuator to impart a controlled uniform strain to the sample. However, for handheld scanning, this adds complexity to the design of the probe and the actuator stroke limits the amount of strain that can be applied. In this work, we present a new volumetric imaging approach that utilizes bidirectional manual compression via the natural motion of the user's hand to induce strain to the sample, realizing compact, actuator-free, handheld compression OCE. In this way, we are able to demonstrate rapid acquisition of three-dimensional quantitative microelastography (QME) datasets of a tissue volume (6 × 6 × 1 mm

Identifiants

pubmed: 32057188
doi: 10.1002/jbio.201960196
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e201960196

Informations de copyright

© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Auteurs

Qi Fang (Q)

BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Crawley, Western Australia, Australia.
Department of Electrical, Electronic and Computer Engineering, School of Engineering, The University of Western Australia, Crawley, Western Australia, Australia.

Luke Frewer (L)

BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Crawley, Western Australia, Australia.
Department of Electrical, Electronic and Computer Engineering, School of Engineering, The University of Western Australia, Crawley, Western Australia, Australia.

Renate Zilkens (R)

BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Crawley, Western Australia, Australia.
Division of Surgery, Medical School, The University of Western Australia, Crawley, Western Australia, Australia.

Brooke Krajancich (B)

BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Crawley, Western Australia, Australia.
Department of Electrical, Electronic and Computer Engineering, School of Engineering, The University of Western Australia, Crawley, Western Australia, Australia.
Department of Electrical Engineering, Stanford University, Stanford, California, USA.

Andrea Curatolo (A)

BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Crawley, Western Australia, Australia.
Department of Electrical, Electronic and Computer Engineering, School of Engineering, The University of Western Australia, Crawley, Western Australia, Australia.
Optics and Biophotonics Group, Visual Instituto de Óptica "Daza de Valdés," Consejo Superior de Investigaciones Cientificas (IO, CSIC), Madrid, Spain.

Lixin Chin (L)

BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Crawley, Western Australia, Australia.
Department of Electrical, Electronic and Computer Engineering, School of Engineering, The University of Western Australia, Crawley, Western Australia, Australia.

Ken Y Foo (KY)

BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Crawley, Western Australia, Australia.
Department of Electrical, Electronic and Computer Engineering, School of Engineering, The University of Western Australia, Crawley, Western Australia, Australia.

Devina D Lakhiani (DD)

BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Crawley, Western Australia, Australia.
Department of Electrical, Electronic and Computer Engineering, School of Engineering, The University of Western Australia, Crawley, Western Australia, Australia.

Rowan W Sanderson (RW)

BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Crawley, Western Australia, Australia.
Department of Electrical, Electronic and Computer Engineering, School of Engineering, The University of Western Australia, Crawley, Western Australia, Australia.

Philip Wijesinghe (P)

BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Crawley, Western Australia, Australia.
Department of Electrical, Electronic and Computer Engineering, School of Engineering, The University of Western Australia, Crawley, Western Australia, Australia.
School of Physics and Astronomy (SUPA), University of St Andrews, St Andrews, UK.

James D Anstie (JD)

BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Crawley, Western Australia, Australia.
Department of Electrical, Electronic and Computer Engineering, School of Engineering, The University of Western Australia, Crawley, Western Australia, Australia.

Benjamin F Dessauvagie (BF)

PathWest, Fiona Stanley Hospital, Murdoch, Western Australia, Australia.
School of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia.

Bruce Latham (B)

PathWest, Fiona Stanley Hospital, Murdoch, Western Australia, Australia.
The University of Notre Dame, Fremantle, Western Australia, Australia.

Christobel M Saunders (CM)

Division of Surgery, Medical School, The University of Western Australia, Crawley, Western Australia, Australia.
Breast Centre, Fiona Stanley Hospital, 11 Robin Warren Drive, Murdoch, Western Australia, Australia.
Breast Clinic, Royal Perth Hospital, Perth, Western Australia, Australia.

Brendan F Kennedy (BF)

BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Crawley, Western Australia, Australia.
Department of Electrical, Electronic and Computer Engineering, School of Engineering, The University of Western Australia, Crawley, Western Australia, Australia.
Australian Research Council Centre for Personalised Therapeutics Technologies, Western Australia, Australia.

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