The Influence of Indentation Deformity on Outcomes With Intralesional Collagenase Clostridium Histolyticum Monotherapy for Peyronie's Disease.


Journal

Urology
ISSN: 1527-9995
Titre abrégé: Urology
Pays: United States
ID NLM: 0366151

Informations de publication

Date de publication:
05 2020
Historique:
received: 29 11 2019
revised: 23 01 2020
accepted: 27 01 2020
pubmed: 15 2 2020
medline: 4 2 2022
entrez: 15 2 2020
Statut: ppublish

Résumé

To identify patient-specific factors associated with patient-reported improvements in functional outcomes after intralesional Collagenase Clostridium histolyticum (CCH) for Peyronie's Disease (PD). We retrospectively explored our prospectively maintained CCH registry. We sought to identify patient-specific factors that prevented the need for surgical straightening and/or improved ability to engage in penetrative intercourse. Eighty-six patients underwent CCH monotherapy and had objective follow-up data available. Mean PD symptom duration was 25 months (SD 44) and baseline curvature was 65 Baseline indentation/hourglass deformity and curve improvement <15

Identifiants

pubmed: 32057793
pii: S0090-4295(20)30126-6
doi: 10.1016/j.urology.2020.01.035
pii:
doi:

Substances chimiques

Antifibrotic Agents 0
Microbial Collagenase EC 3.4.24.3

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

122-128

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Matthew J Ziegelmann (MJ)

Department of Urology, Mayo Clinic, Rochester, MN. Electronic address: Ziegelmann.Matthew@mayo.edu.

Daniel Heslop (D)

Department of Urology, Mayo Clinic, Rochester, MN.

Matthew Houlihan (M)

Department of Urology, Mayo Clinic, Rochester, MN.

Petar Bajic (P)

Division of Urology, Rush University Medical Center, Chicago, IL.

Sevann Helo (S)

Department of Urology, Mayo Clinic, Rochester, MN.

Landon Trost (L)

Division of Urology, Rush University Medical Center, Chicago, IL.

Tobias Kohler (T)

Department of Urology, Mayo Clinic, Rochester, MN.

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Classifications MeSH