[Adverse obstetric and perinatal outcome with in vitro fertilization technology: A French nationwide population-based study].
Risques de morbidité maternelle et périnatale en fécondation in vitro : une étude nationale de cohorte française.
Adult
Cohort Studies
Congenital Abnormalities
/ epidemiology
Female
Fertilization in Vitro
/ statistics & numerical data
France
/ epidemiology
Humans
Infant, Newborn
Infant, Small for Gestational Age
Pregnancy
Pregnancy Complications
/ epidemiology
Pregnancy Outcome
/ epidemiology
Premature Birth
/ epidemiology
Young Adult
Birth defect
Fécondation in vitro
Hypotrophie
In vitro fertilization
Malformations congénitales
Morbidité maternelle
Pregnancy complication
Preterm birth
Prématurité
Small for gestational age
Journal
Gynecologie, obstetrique, fertilite & senologie
ISSN: 2468-7189
Titre abrégé: Gynecol Obstet Fertil Senol
Pays: France
ID NLM: 101693805
Informations de publication
Date de publication:
04 2020
04 2020
Historique:
received:
14
10
2019
pubmed:
15
2
2020
medline:
6
5
2021
entrez:
15
2
2020
Statut:
ppublish
Résumé
The objective of this study was to quantify the risk of maternal and perinatal morbidity with in vitro fertilization (IVF) technology compared to non-IVF pregnancies in a recent French national cohort. The data was extracted from the hospital information data system, including all pregnancies with a delivery from 2013 to 2016. The risks of preterm birth, maternal morbidity (venous and arterial thrombosis, gestational diabetes, vascular disorders, placenta previa, placenta abruption), hypotrophy and congenital malformation were compared in both groups in univariate and multivariate analysis after adjustment on the characteristics of women (age, parity, obesity, tobacco dependence, history of diabetes or high blood pressure), multiple deliveries and sex of children. In all, 2,875,662 pregnancies and 2,922,712 births were analyzed, of which 49,224 were derived from IVF (1.7%). In multivariate analysis, all risks were significantly higher in IVF: premature deliveries (OR The results of this study on a large cohort of recent births in France confirm that there was an increased risk of maternal and perinatal morbidities in IVF. These risks were similar to those published in the international literature. This study is the starting point for a forthcoming surveillance.
Identifiants
pubmed: 32058045
pii: S2468-7189(20)30051-9
doi: 10.1016/j.gofs.2020.02.002
pii:
doi:
Types de publication
Journal Article
Langues
fre
Sous-ensembles de citation
IM
Pagination
351-358Informations de copyright
Copyright © 2020 Elsevier Masson SAS. All rights reserved.