Minimally Invasive Spinal Deformity Surgery: Analysis of Patients Who Fail to Reach Minimal Clinically Important Difference.


Journal

World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275

Informations de publication

Date de publication:
05 2020
Historique:
received: 02 11 2019
revised: 03 02 2020
accepted: 04 02 2020
pubmed: 16 2 2020
medline: 18 8 2020
entrez: 16 2 2020
Statut: ppublish

Résumé

It is well known that clinical improvements following surgical intervention are variable. While all surgeons strive to maximize reliability and degree of improvement, certain patients will fail to achieve meaningful gains. We aim to analyze patients who failed to reach minimal clinically important difference (MCID) in an effort to improve outcomes for minimally invasive deformity surgery. Data were collected on a multicenter registry of minimally invasive surgery adult spinal deformity surgeries. Patient inclusion criteria were age ≥18 years, coronal Cobb ≥20 degrees, pelvic incidence-lumbar lordosis ≥10 degrees, or a sagittal vertical axis >5 cm. All patients had minimum 2 years' follow-up (N = 222). MCID was defined as 12.8 or more points of improvement in the Oswestry Disability Index. Up to 2 different etiologies for failure were allowed per patient. We identified 78 cases (35%) where the patient failed to achieve MCID at long-term follow-up. A total of 82 identifiable causes were seen in these patients with 14 patients having multiple causes. In 6 patients, the etiology was unclear. The causes were subclassified as neurologic, medical, structural, under treatment, degenerative progression, traumatic, idiopathic, and floor effects. In 71% of cases, an identifiable cause was related to the spine, whereas in 35% the cause was not related to the spine. Definable causes of failed MIS ASD surgery are often identifiable and similar to open surgery. In some cases the cause is treatable and structural. However, it is also common to see failure due to pathologies unrelated to the index surgery.

Sections du résumé

BACKGROUND
It is well known that clinical improvements following surgical intervention are variable. While all surgeons strive to maximize reliability and degree of improvement, certain patients will fail to achieve meaningful gains. We aim to analyze patients who failed to reach minimal clinically important difference (MCID) in an effort to improve outcomes for minimally invasive deformity surgery.
METHODS
Data were collected on a multicenter registry of minimally invasive surgery adult spinal deformity surgeries. Patient inclusion criteria were age ≥18 years, coronal Cobb ≥20 degrees, pelvic incidence-lumbar lordosis ≥10 degrees, or a sagittal vertical axis >5 cm. All patients had minimum 2 years' follow-up (N = 222). MCID was defined as 12.8 or more points of improvement in the Oswestry Disability Index. Up to 2 different etiologies for failure were allowed per patient.
RESULTS
We identified 78 cases (35%) where the patient failed to achieve MCID at long-term follow-up. A total of 82 identifiable causes were seen in these patients with 14 patients having multiple causes. In 6 patients, the etiology was unclear. The causes were subclassified as neurologic, medical, structural, under treatment, degenerative progression, traumatic, idiopathic, and floor effects. In 71% of cases, an identifiable cause was related to the spine, whereas in 35% the cause was not related to the spine.
CONCLUSIONS
Definable causes of failed MIS ASD surgery are often identifiable and similar to open surgery. In some cases the cause is treatable and structural. However, it is also common to see failure due to pathologies unrelated to the index surgery.

Identifiants

pubmed: 32059971
pii: S1878-8750(20)30290-4
doi: 10.1016/j.wneu.2020.02.025
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e499-e505

Informations de copyright

Copyright © 2020. Published by Elsevier Inc.

Auteurs

Michael Y Wang (MY)

Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA. Electronic address: MWang2@med.miami.edu.

Juan Uribe (J)

Department of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona, USA.

Praveen V Mummaneni (PV)

Department of Neurological Surgery, University of California, San Francisco, California, USA.

Stacie Tran (S)

Department of Orthopedic Surgery, San Diego Center for Spinal Disorders, La Jolla, USA.

G Damian Brusko (GD)

Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.

Paul Park (P)

Department of Neurological Surgery, University of Michigan, Ann Arbor, Michigan, USA.

Pierce Nunley (P)

Department of Orthopedic Surgery, Spine Institute of Louisiana, Shreveport, Louisiana, USA.

Adam Kanter (A)

Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

David Okonkwo (D)

Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Neel Anand (N)

Department of Orthopedic Surgery, Cedars Sinai Hospital, Los Angeles, California, USA.

Dean Chou (D)

Department of Neurological Surgery, University of California, San Francisco, California, USA.

Christopher I Shaffrey (CI)

Department of Neurological Surgery, Duke University, Durham, North Carolina, USA.

Kai-Ming Fu (KM)

Department of Orthopedic Surgery, Weill Cornell Medical College, New York, New York, USA.

Gregory M Mundis (GM)

Department of Orthopedic Surgery, Scripps Clinic Torrey Pines, La Jolla, USA.

Robert Eastlack (R)

Department of Neurological Surgery, Scripps Clinic Torrey Pines, La Jolla, USA.

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