Abnormal gut motility in inflammatory bowel disease: an update.

Crohn’s disease Gut dysmotility Inflammatory bowel disease Ulcerative colitis

Journal

Techniques in coloproctology
ISSN: 1128-045X
Titre abrégé: Tech Coloproctol
Pays: Italy
ID NLM: 9613614

Informations de publication

Date de publication:
04 2020
Historique:
received: 09 11 2019
accepted: 07 02 2020
pubmed: 18 2 2020
medline: 28 4 2021
entrez: 17 2 2020
Statut: ppublish

Résumé

There is substantial evidence linking disturbed gastrointestinal motility to inflammation. Thus, it is not surprising that abnormalities of gastrointestinal motility play a role in inflammatory bowel disease (IBD), affecting patient outcomes. We performed a review of the literature to investigate the relationship between abnormal gut motility and IBD. With an extensive literature search, we retrieved the pertinent articles linking disturbed gut motility to IBD in various anatomical districts. The evidence in the literature suggests that abnormal gastrointestinal motility plays a role in the clinical setting of IBD and may confuse the clinical picture. Abnormal gut motility may be important in the clinical setting of IBD. However, additional data obtained with modern techniques (e.g., magnetic resonance imaging) are needed to individuate in a more precise manner gastrointestinal motor dysfunctions, to understand the nature of clinical manifestations and properly tailor the treatment of patients.

Sections du résumé

BACKGROUND
There is substantial evidence linking disturbed gastrointestinal motility to inflammation. Thus, it is not surprising that abnormalities of gastrointestinal motility play a role in inflammatory bowel disease (IBD), affecting patient outcomes. We performed a review of the literature to investigate the relationship between abnormal gut motility and IBD.
METHODS
With an extensive literature search, we retrieved the pertinent articles linking disturbed gut motility to IBD in various anatomical districts.
RESULTS
The evidence in the literature suggests that abnormal gastrointestinal motility plays a role in the clinical setting of IBD and may confuse the clinical picture.
CONCLUSIONS
Abnormal gut motility may be important in the clinical setting of IBD. However, additional data obtained with modern techniques (e.g., magnetic resonance imaging) are needed to individuate in a more precise manner gastrointestinal motor dysfunctions, to understand the nature of clinical manifestations and properly tailor the treatment of patients.

Identifiants

pubmed: 32062797
doi: 10.1007/s10151-020-02168-y
pii: 10.1007/s10151-020-02168-y
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

275-282

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Auteurs

G Bassotti (G)

Gastroenterology and Hepatology Section, Department of Medicine, University of Perugia Medical School, Perugia, Italy. gabassot@tin.it.
Clinica Di Gastroenterologia Ed Epatologia, Ospedale Santa Maria della Misericordia, Piazzale Menghini, 1, San Sisto, 06156, Perugia, Italy. gabassot@tin.it.

E Antonelli (E)

Gastroenterology Unit, Perugia General Hospital, Perugia, Italy.

V Villanacci (V)

Pathology Institute, Spedali Civili, Brescia, Italy.

R Nascimbeni (R)

Surgical Section Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.

M P Dore (MP)

Department of Medical, Surgical, and Experimental Sciences, University of Sassari, Sassari, Italy.

G M Pes (GM)

Department of Medical, Surgical, and Experimental Sciences, University of Sassari, Sassari, Italy.

G Maconi (G)

Gastroenterology Unit, Department of Biomedical and Clinical Sciences, L. Sacco University Hospital, Milan, Italy.

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