Dubin-Johnson Syndrome Presenting During Cardiac Transplantation Evaluation.
cardiac surgery
dubin johnson syndrome
hyperbilirubinemia
liver biopsy
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
08 Jan 2020
08 Jan 2020
Historique:
entrez:
18
2
2020
pubmed:
18
2
2020
medline:
18
2
2020
Statut:
epublish
Résumé
Dubin-Johnson syndrome is a rare, benign disorder that results in conjugated hyperbilirubinemia. The disease manifests as intermittent jaundice without long-term hepatic or other clinical complications. This article reports a case of Dubin-Johnson syndrome, which was identified during cardiac transplant evaluation for cardiomyopathy secondary to a polyglycogen storage disease. The patient successfully underwent an orthotopic heart transplant. Postoperatively, her conjugated hyperbilirubinemia increased as compared to her baseline but resolved after several weeks. This report briefly reviews the hepatic manifestations in patients with Dubin-Johnson syndrome undergoing major surgery and highlights urinary coproporphyrin as a useful diagnostic test for Dubin-Johnson syndrome.
Identifiants
pubmed: 32064176
doi: 10.7759/cureus.6594
pmc: PMC7003716
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e6594Informations de copyright
Copyright © 2020, LeVee et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Am J Med. 1958 Feb;24(2):268-92
pubmed: 13508683
J Pediatr. 2018 May;196:161-167.e1
pubmed: 29499989
Pediatr Res. 2016 Mar;79(3):378-86
pubmed: 26595536
Thorax. 1974 Jan;29(1):68-74
pubmed: 4825554
J Thorac Cardiovasc Surg. 1973 Apr;65(4):559-62
pubmed: 4697446
Nihon Kyobu Geka Gakkai Zasshi. 1985 Sep;33(9):1380-2
pubmed: 4078398
Yonsei Med J. 1990 Mar;31(1):27-32
pubmed: 2346038