In vitro maturation is a viable option for urgent fertility preservation in young women with hematological conditions.
fertility preservation
in vitro maturation
lymphoma
oocyte freezing
Journal
Hematological oncology
ISSN: 1099-1069
Titre abrégé: Hematol Oncol
Pays: England
ID NLM: 8307268
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
07
01
2020
revised:
04
02
2020
accepted:
12
02
2020
pubmed:
18
2
2020
medline:
3
11
2020
entrez:
18
2
2020
Statut:
ppublish
Résumé
Fertility preservation embraces different techniques developed to improve young women chances of becoming mothers after healing. Among them, in vitro maturation (IVM) procedure is based on oocyte retrieval without any gonadotropin treatment, feasible under locoregional or local anesthesia, with very low operative complications. The present retrospective analysis of a preliminary case series of 25 women diagnosed with Hodgkin or non-Hodgkin lymphoma aims to evaluate the feasibility of IVM for urgent fertility preservation purposes in hematological context. A median of five mature oocytes was cryopreserved after one cycle of IVM, performed without delaying the start of the chemotherapy (median delay from histological diagnosis to start of the chemotherapy 17.5 days). No association was found between lymphomas' characteristics and the number of recovered or frozen oocytes. Although experimental, this technique could be relevant when fertility preservation has to be performed within a short time frame and without additional surgery nor any risk of malignant cells reintroduction.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
560-564Informations de copyright
© 2020 John Wiley & Sons Ltd.
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