Key amino acid residues involved in mammalian and insecticidal activities of Magi4 and Hv1b, cysteine-rich spider peptides from the δ-atracotoxin family.
Core-domain
NC-domain
Recombinant expression
Spider
δ-Atracotoxin
Journal
Amino acids
ISSN: 1438-2199
Titre abrégé: Amino Acids
Pays: Austria
ID NLM: 9200312
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
received:
06
12
2019
accepted:
31
01
2020
pubmed:
19
2
2020
medline:
28
11
2020
entrez:
19
2
2020
Statut:
ppublish
Résumé
δ-Atracotoxins, also known as δ-hexatoxins, are spider neurotoxic peptides, lethal to both vertebrates and insects. Their mechanism of action involves the binding to of the S3/S4 loop of the domain IV of the voltage-gated sodium channels (Na
Identifiants
pubmed: 32067123
doi: 10.1007/s00726-020-02825-4
pii: 10.1007/s00726-020-02825-4
doi:
Substances chimiques
Amino Acids
0
Insecticides
0
Neurotoxins
0
Recombinant Proteins
0
Spider Venoms
0
delta-atracotoxin-HV1
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
465-475Subventions
Organisme : Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México
ID : IN203118
Organisme : FORDECYT -CONACyT "Venenos/Antivenenos"
ID : 303045