Standardized Definitions of Bleeding After Transbronchial Lung Biopsy: A Delphi Consensus Statement From the Nashville Working Group.


Journal

Chest
ISSN: 1931-3543
Titre abrégé: Chest
Pays: United States
ID NLM: 0231335

Informations de publication

Date de publication:
07 2020
Historique:
received: 22 09 2019
revised: 03 12 2019
accepted: 25 01 2020
pubmed: 19 2 2020
medline: 22 5 2021
entrez: 19 2 2020
Statut: ppublish

Résumé

Transbronchial lung biopsies are commonly performed for a variety of indications. Although generally well tolerated, complications such as bleeding do occur. Description of bleeding severity is crucial both clinically and in research trials; to date, there is no validated scale that is widely accepted for this purpose. Can a simple, reproducible tool for categorizing the severity of bleeding after transbronchial biopsy be created? Using the modified Delphi method, an international group of bronchoscopists sought to create a new scale tailored to assess bleeding severity among patients undergoing flexible bronchoscopy with transbronchial lung biopsies. Cessation criteria were specified a priori and included reaching > 80% consensus among the experts or three rounds, whichever occurred first. Thirty-six expert bronchoscopists from eight countries, both in academic and community practice settings, participated in the creation of the scale. After the live meeting, two iterations were made. The second and final scale was vetted by all 36 participants, with a weighted average of 4.47/5; 53% were satisfied, and 47% were very satisfied. The panel reached a consensus and proposes the Nashville Bleeding Scale. The use of a simplified airway bleeding scale that can be applied at bedside is an important, necessary tool for categorizing the severity of bleeding. Uniformity in reporting clinically significant airway bleeding during bronchoscopic procedures will improve the quality of the information derived and could lead to standardization of management. In addition to transbronchial biopsies, this scale could also be applied to other bronchoscopic procedures, such as endobronchial biopsy or endobronchial ultrasound-guided needle aspiration.

Sections du résumé

BACKGROUND
Transbronchial lung biopsies are commonly performed for a variety of indications. Although generally well tolerated, complications such as bleeding do occur. Description of bleeding severity is crucial both clinically and in research trials; to date, there is no validated scale that is widely accepted for this purpose. Can a simple, reproducible tool for categorizing the severity of bleeding after transbronchial biopsy be created?
METHODS
Using the modified Delphi method, an international group of bronchoscopists sought to create a new scale tailored to assess bleeding severity among patients undergoing flexible bronchoscopy with transbronchial lung biopsies. Cessation criteria were specified a priori and included reaching > 80% consensus among the experts or three rounds, whichever occurred first.
RESULTS
Thirty-six expert bronchoscopists from eight countries, both in academic and community practice settings, participated in the creation of the scale. After the live meeting, two iterations were made. The second and final scale was vetted by all 36 participants, with a weighted average of 4.47/5; 53% were satisfied, and 47% were very satisfied. The panel reached a consensus and proposes the Nashville Bleeding Scale.
CONCLUSIONS
The use of a simplified airway bleeding scale that can be applied at bedside is an important, necessary tool for categorizing the severity of bleeding. Uniformity in reporting clinically significant airway bleeding during bronchoscopic procedures will improve the quality of the information derived and could lead to standardization of management. In addition to transbronchial biopsies, this scale could also be applied to other bronchoscopic procedures, such as endobronchial biopsy or endobronchial ultrasound-guided needle aspiration.

Identifiants

pubmed: 32067944
pii: S0012-3692(20)30272-5
doi: 10.1016/j.chest.2020.01.036
pmc: PMC7403751
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

393-400

Subventions

Organisme : NIGMS NIH HHS
ID : P20 GM125498
Pays : United States

Informations de copyright

Copyright © 2020. Published by Elsevier Inc.

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Auteurs

Erik E Folch (EE)

Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA. Electronic address: efolch@mgh.harvard.edu.

Amit K Mahajan (AK)

INOVA Medical Group, Falls Church, VA.

Catherine L Oberg (CL)

Division of Pulmonary, Critical Care Medicine, Clinical Immunology, and Allergy, David Geffen School of Medicine at UCLA, Los Angeles, CA.

Fabien Maldonado (F)

Vanderbilt University Medical Center, Nashville, TN.

Eric Toloza (E)

Moffitt Cancer Center, Tampa, FL.

William S Krimsky (WS)

MedStar Franklin Square Medical Center, Baltimore, MD.

Scott Oh (S)

Division of Pulmonary, Critical Care Medicine, Clinical Immunology, and Allergy, David Geffen School of Medicine at UCLA, Los Angeles, CA.

Mark R Bowling (MR)

Division of Pulmonary, Critical Care, and Sleep Medicine, East Carolina University, Greenville, NC.

Sadia Benzaquen (S)

University of Cincinnati, Cincinnati, OH.

Charles M Kinsey (CM)

University of Vermont, Burlington, VT.

Atul C Mehta (AC)

Cleveland Clinic Health System, Cleveland, OH.

Sebastian Fernandez-Bussy (S)

Mayo Clinic Hospital Jacksonville, Jacksonville, FL.

Javier Flandes (J)

Interventional Pulmonology Service, Hospital Universitario Fundacion Jimenez Diaz, Universidad Autonoma de Madrid, Madrid, Spain.

Kelvin Lau (K)

Barts Health NHS Trust, London, England.

Ganesh Krishna (G)

Palo Alto Medical Foundation, Palo Alto, CA.

Michael A Nead (MA)

University of Rochester, Rochester, NY.

Felix Herth (F)

Department of Pneumology and Critical Care Medicine, Thoraxklinik University of Heidelberg, Heidelberg, Germany.

Alejandro A Aragaki-Nakahodo (AA)

University of Cincinnati, Cincinnati, OH.

Emanuela Barisione (E)

Interventional Pulmonology Unit, IRCCS San Martino Hospital-IST National Cancer Research Institute, Genoa, Italy.

Sandeep Bansal (S)

Lancaster General Hospital, Lancaster, PA.

Dragos Zanchi (D)

Pulmonary and Sleep of Tampa Bay Inc, Wesley Chapel, FL.

Michael Zgoda (M)

University Pulmonary Associates, Charlotte, NC.

Peter O Lutz (PO)

Pulmonary Associates of Mobile, Daphne, AL.

Robert J Lentz (RJ)

Vanderbilt University Medical Center, Nashville, TN.

Christopher Parks (C)

Cancer Treatment Centers of America, Atlanta, GA.

Mario Salio (M)

IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Kenneth Perret (K)

Shannon Medical Center, San Angelo, TX.

Colleen Keyes (C)

Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA.

Gregory P LeMense (GP)

Blount Memorial Hospital, Maryville, TN.

John D Hinze (JD)

Seton Healthcare Family, Austin, TX.

Adnan Majid (A)

Division of Thoracic Surgery and Interventional Pulmonology, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA.

Merete Christensen (M)

Rigshospitalet, Copenhagen, Denmark.

Jordan Kazakov (J)

Brigham and Women's Hospital, Boston, MA.

Gonzalo Labarca (G)

Department of Internal Medicine, Pontifical Catholic University, Santiago, Chile.

Ernest Waller (E)

Blount Memorial Hospital, Maryville, TN.

Michael Studnicka (M)

Department of Pulmonary Medicine, the Paracelsus Medical University, Salzburg, Austria.

Catalina V Teba (CV)

University Hospitals of Cleveland, Cleveland, OH.

Sandeep J Khandhar (SJ)

Virginia Cancer Specialists PC, Fairfax, VA.

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