Pre-Analytical and Analytical Variables of Label-Independent Enrichment and Automated Detection of Circulating Tumor Cells in Cancer Patients.

CTC Parsortix cancer metastasis circulating tumor cells enrichment

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
13 Feb 2020
Historique:
received: 06 01 2020
revised: 10 02 2020
accepted: 11 02 2020
entrez: 20 2 2020
pubmed: 20 2 2020
medline: 20 2 2020
Statut: epublish

Résumé

Circulating tumor cells (CTCs) are promising tools for risk prediction and the monitoring of response to therapy in cancer patients. Within the EU/IMI CANCER-ID consortium, we validated CTC enrichment systems for future inclusion into clinical trials. Due to the known heterogeneity of markers expressed on CTCs, we tested the Parsortix

Identifiants

pubmed: 32069934
pii: cancers12020442
doi: 10.3390/cancers12020442
pmc: PMC7072175
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : European Research Council
ID : 834974
Pays : International
Organisme : Innovative Medicines Initiative
ID : 115749
Organisme : H2020 Marie Skłodowska-Curie Actions
ID : 765492

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Auteurs

Claudia Koch (C)

Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Simon A Joosse (SA)

Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Svenja Schneegans (S)

Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Okka J W Wilken (OJW)

Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Melanie Janning (M)

Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Department of Oncology, Hematology and Bone Marrow Transplantation with section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Desiree Loreth (D)

Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Volkmar Müller (V)

Department of Gynecology and Gynecologic Oncology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Katharina Prieske (K)

Department of Gynecology and Gynecologic Oncology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Malgorzata Banys-Paluchowski (M)

Department of Gynecology, Asklepios Clinic Barmbek, 22307 Hamburg, Germany.
Department of Gynecology and Obstetrics, Marienkrankenhaus Hamburg, 22087 Hamburg, Germany.

Ludwig J Horst (LJ)

Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Sonja Loges (S)

Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Department of Oncology, Hematology and Bone Marrow Transplantation with section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Sven Peine (S)

Department of Transfusion Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Harriet Wikman (H)

Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Tobias M Gorges (TM)

Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Klaus Pantel (K)

Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Classifications MeSH