Saccular Aneurysm Models Featuring Growth and Rupture: A Systematic Review.
aneurysm rupture
animal model
growth
intracranial aneurysm
saccular
Journal
Brain sciences
ISSN: 2076-3425
Titre abrégé: Brain Sci
Pays: Switzerland
ID NLM: 101598646
Informations de publication
Date de publication:
13 Feb 2020
13 Feb 2020
Historique:
received:
15
01
2020
accepted:
25
01
2020
entrez:
20
2
2020
pubmed:
20
2
2020
medline:
20
2
2020
Statut:
epublish
Résumé
Most available large animal extracranial aneurysm models feature healthy non-degenerated aneurysm pouches with stable long-term follow-ups and extensive healing reactions after endovascular treatment. This review focuses on a small subgroup of extracranial aneurysm models that demonstrated growth and potential rupture during follow-up. The literature was searched in Medline/Pubmed to identify extracranial in vivo saccular aneurysm models featuring growth and rupture, using a predefined search strategy in accordance with the PRISMA guidelines. From eligible studies we extracted the following details: technique and location of aneurysm creation, aneurysm pouch characteristics, time for model creation, growth and rupture rate, time course, patency rate, histological findings, and associated morbidity and mortality. A total of 20 articles were found to describe growth and/or rupture of an experimentally created extracranial saccular aneurysm during follow-up. Most frequent growth was reported in rats ( Extracranial saccular aneurysm models with growth and rupture are rare. Degradation of the created aneurysmal outpouch seems to be a prerequisite to allow growth, which may ultimately lead to rupture. Since it has been shown that the aneurysm wall is important for healing after endovascular therapy, it is likely that models featuring growth and rupture will gain in interest for preclinical testing of novel endovascular therapies.
Sections du résumé
BACKGROUND
BACKGROUND
Most available large animal extracranial aneurysm models feature healthy non-degenerated aneurysm pouches with stable long-term follow-ups and extensive healing reactions after endovascular treatment. This review focuses on a small subgroup of extracranial aneurysm models that demonstrated growth and potential rupture during follow-up.
METHODS
METHODS
The literature was searched in Medline/Pubmed to identify extracranial in vivo saccular aneurysm models featuring growth and rupture, using a predefined search strategy in accordance with the PRISMA guidelines. From eligible studies we extracted the following details: technique and location of aneurysm creation, aneurysm pouch characteristics, time for model creation, growth and rupture rate, time course, patency rate, histological findings, and associated morbidity and mortality.
RESULTS
RESULTS
A total of 20 articles were found to describe growth and/or rupture of an experimentally created extracranial saccular aneurysm during follow-up. Most frequent growth was reported in rats (
CONCLUSIONS
CONCLUSIONS
Extracranial saccular aneurysm models with growth and rupture are rare. Degradation of the created aneurysmal outpouch seems to be a prerequisite to allow growth, which may ultimately lead to rupture. Since it has been shown that the aneurysm wall is important for healing after endovascular therapy, it is likely that models featuring growth and rupture will gain in interest for preclinical testing of novel endovascular therapies.
Identifiants
pubmed: 32069946
pii: brainsci10020101
doi: 10.3390/brainsci10020101
pmc: PMC7071455
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
J Zhejiang Univ Sci B. 2007 Oct;8(10):697-703
pubmed: 17910110
AJNR Am J Neuroradiol. 2013 Feb;34(2):346-53
pubmed: 23153870
Ann Surg. 1953 Aug;138(2):216-8
pubmed: 13066011
Stroke. 2003 Jun;34(6):1398-403
pubmed: 12775880
Stroke. 2013 Feb;44(2):442-7
pubmed: 23321438
Neurosurgery. 2006 May;58(5):936-44; discussion 936-44
pubmed: 16639330
Microsurgery. 1987;8(3):128-37
pubmed: 3670035
Surg Neurol. 1976 Jan;5(1):15-8
pubmed: 1265619
Neurol Res. 1990 Dec;12(4):260-3
pubmed: 1982171
Interv Neuroradiol. 2012 Dec;18(4):391-400
pubmed: 23217634
J Neurointerv Surg. 2018 Apr;10(4):411-415
pubmed: 28768819
Neurosurgery. 2007 Jun;60(6):1119-27; discussion 1127-8
pubmed: 17538387
J Clin Neurosci. 2014 Sep;21(9):1514-9
pubmed: 24929861
AJNR Am J Neuroradiol. 1993 Jul-Aug;14(4):801-3
pubmed: 8352147
Stroke. 2014 Dec;45(12):3684-90
pubmed: 25370586
Neurosurg Focus. 2019 Jul 1;47(1):E20
pubmed: 31261125
Surg Neurol. 1990 Jul;34(1):3-7
pubmed: 2360161
AJNR Am J Neuroradiol. 2010 May;31(5):967-71
pubmed: 20019111
J Neurointerv Surg. 2014 Jan;6(1):29-31
pubmed: 23256990
J Neurosurg. 1964 Dec;21:1067-9
pubmed: 14293798
AJNR Am J Neuroradiol. 2001 Apr;22(4):698-703
pubmed: 11290481
AJNR Am J Neuroradiol. 2010 Mar;31(3):418-23
pubmed: 19875466
Surg Gynecol Obstet. 1979 Jul;149(1):43-8
pubmed: 451826
J Neuroradiol. 1999 Mar;26(1):7-20
pubmed: 10363438
Neurosurg Rev. 2019 Mar;42(1):49-58
pubmed: 28819834
J Neurosurg. 1961 Nov;18:741-5
pubmed: 14006529
Acta Neuropathol. 2012 Jun;123(6):773-86
pubmed: 22249619
AJNR Am J Neuroradiol. 2008 Jun;29(6):1067-70
pubmed: 18388214
Neurology. 2013 Jun 4;80(23):2154-65
pubmed: 23733552
Stroke. 2003 Aug;34(8):2031-7
pubmed: 12869719
Neurol Res. 1994 Dec;16(6):425-7
pubmed: 7708131
Stroke. 2014 Jan;45(1):248-54
pubmed: 24222045
Surg Neurol. 2001 Feb;55(2):116-22
pubmed: 11301098
Microsurgery. 1996;17(12):681-9
pubmed: 9588713