Effectiveness of a pharmaceutical instruction video for adherence to dermatopathy treatment in patients with cancer receiving the anti-epidermal growth factor receptor antibody.


Journal

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
ISSN: 1477-092X
Titre abrégé: J Oncol Pharm Pract
Pays: England
ID NLM: 9511372

Informations de publication

Date de publication:
Oct 2020
Historique:
pubmed: 20 2 2020
medline: 8 1 2021
entrez: 20 2 2020
Statut: ppublish

Résumé

Dermatopathy develops as a side effect in patients receiving anti-epidermal growth factor receptor antibody treatment. Topical moisturizers are used for the prevention and treatment of this dermatopathy. Active participation of patients in their own treatment is important for the appropriate application of topical preparations. We prepared a pharmaceutical instructional video for adhering to the topical application protocol. In this study, we investigated the effectiveness of this pharmaceutical instructional video on treatment adherence. Study participants were patients with cancer receiving the anti-epidermal growth factor receptor antibody for the first time. A pharmacist instructed the patients on how to use the pharmaceutical instruction video. Daily topical preparation use following the video demonstration was assessed. The effectiveness of the pharmaceutical instruction video was evaluated by assessing the adherence of patients who did not use the pharmaceutical instruction video for the past 2 periods (26 months; controls 1 and 2). The incidence of side effects was compared between the two control groups and the group of patients who received the pharmaceutical instruction video. The amount of topical preparation consumed (median, g/day) by patients who received patient compliance instructions using the pharmaceutical instruction video was 9.8 g/day, as compared with control group 1 (4.5 g/day) and control group 2 (5.5 g/day) ( The use of visual instructional media for patient compliance by pharmacists may be effective in maintaining and improving treatment adherence.

Sections du résumé

BACKGROUND BACKGROUND
Dermatopathy develops as a side effect in patients receiving anti-epidermal growth factor receptor antibody treatment. Topical moisturizers are used for the prevention and treatment of this dermatopathy. Active participation of patients in their own treatment is important for the appropriate application of topical preparations. We prepared a pharmaceutical instructional video for adhering to the topical application protocol. In this study, we investigated the effectiveness of this pharmaceutical instructional video on treatment adherence.
METHODS METHODS
Study participants were patients with cancer receiving the anti-epidermal growth factor receptor antibody for the first time. A pharmacist instructed the patients on how to use the pharmaceutical instruction video. Daily topical preparation use following the video demonstration was assessed. The effectiveness of the pharmaceutical instruction video was evaluated by assessing the adherence of patients who did not use the pharmaceutical instruction video for the past 2 periods (26 months; controls 1 and 2). The incidence of side effects was compared between the two control groups and the group of patients who received the pharmaceutical instruction video.
RESULTS RESULTS
The amount of topical preparation consumed (median, g/day) by patients who received patient compliance instructions using the pharmaceutical instruction video was 9.8 g/day, as compared with control group 1 (4.5 g/day) and control group 2 (5.5 g/day) (
CONCLUSION CONCLUSIONS
The use of visual instructional media for patient compliance by pharmacists may be effective in maintaining and improving treatment adherence.

Identifiants

pubmed: 32070210
doi: 10.1177/1078155220904149
doi:

Substances chimiques

Antineoplastic Agents 0
ErbB Receptors EC 2.7.10.1

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1667-1675

Auteurs

Junya Sato (J)

Department of Pharmacy, Shizuoka Cancer Center, Shizuoka, Japan.
Department of Pharmacy, International University of Health and Welfare, Ōtawara, Japan.

Hiroshi Ishikawa (H)

Department of Pharmacy, Shizuoka Cancer Center, Shizuoka, Japan.

Yoko Yasuda (Y)

Department of Pharmacy, Shizuoka Cancer Center, Shizuoka, Japan.

Rei Tanaka (R)

Department of Pharmacy, Shizuoka Cancer Center, Shizuoka, Japan.
Faculty of Pharmaceutical Sciences, Tokyo University of Science, Shinjuku City, Japan.

Yoshio Kiyohara (Y)

Department of Dermatology, Shizuoka Cancer Center, Shizuoka, Japan.

Yuki Yamawaki (Y)

Department of Drug Discovery Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Megumi Endo (M)

Oshika Pharmacy KRAFT, Inc., Tochigi, Japan.

Michihiro Shino (M)

Department of Pharmacy, Shizuoka Cancer Center, Shizuoka, Japan.

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Classifications MeSH