In vitro fermentation of Gracilaria lemaneiformis sulfated polysaccharides and its agaro-oligosaccharides by human fecal inocula and its impact on microbiota.
Agaro-oligosaccharide
Gracilaria lemaneiformis
Gut microbiota
In vitro fermentation
Sulfated polysaccharide
Journal
Carbohydrate polymers
ISSN: 1879-1344
Titre abrégé: Carbohydr Polym
Pays: England
ID NLM: 8307156
Informations de publication
Date de publication:
15 Apr 2020
15 Apr 2020
Historique:
received:
19
11
2019
revised:
18
01
2020
accepted:
18
01
2020
entrez:
20
2
2020
pubmed:
20
2
2020
medline:
22
10
2020
Statut:
ppublish
Résumé
The fermentation behaviour of sulfated polysaccharides (GLP) and their agaro-oligosaccharides (GLO) derived from Gracilaria lemaneiformis were examined. During in vitro fermentation, GLP and GLO increased the concentrations of short chain fatty acids (SCFAs) and modulated the composition and diversity of gut microorganisms compared with control groups. GLP increased the abundance of Bacteroidetes and decreased the abundance of Firmicutes, while GLO increased the abundance of Firmicutes and Actinobacteria. Moreover, the abundances of potential pathogenic bacteria were reduced. Molecular weight and intrinsic viscosity of GLP decreased significantly from 2.15 × 10
Identifiants
pubmed: 32070514
pii: S0144-8617(20)30068-0
doi: 10.1016/j.carbpol.2020.115894
pii:
doi:
Substances chimiques
Polysaccharides
0
Sulfates
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
115894Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare no conflict of interest.